Evidence map›Paper›PMID 36851600›Full record

ArticleViruses2023

Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ.

Jessica Spring, Vera Beilinson, Brian C DeFelice, Juan M Sanchez, Michael Fischbach, Alexander Chervonsky, Tatyana Golovkina

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jessica SpringCommittee on Microbiology, University of Chicago, Chicago, IL 60637, USA.
Vera BeilinsonDepartment of Microbiology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-1259-733X
Brian C DeFeliceChan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Juan M SanchezChan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Michael FischbachDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.
Alexander ChervonskyCommittee on Microbiology, University of Chicago, Chicago, IL 60637, USA.
Tatyana GolovkinaCommittee on Microbiology, University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-2924-6747
University of Chicago · USChan Zuckerberg Initiative (United States) · USStanford University · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI KUNLE ODUNSI · 1985 to 2026
$122.1M
ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI CHANG, EUGENE B · 1990 to 2025
$29.8M
Molecular And Cellular Biology Training ProgramT32GM007183 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S, RICE, PHOEBE A · 1985 to 2021
$23.9M
Virally-induced tumorigenesis controlled by the microbiotaR01CA232882 · NCI · UNIVERSITY OF CHICAGO · PI Tatyana V Golovkina · 2019 to 2026
$3.5M
NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA232882NCI NIH HHS R01CA232882NIDDK NIH HHS P30 DK042086NIGMS NIH HHS T32 GM007183
6 · The paper itself

Abstract

Both viruses and bacteria produce "pathogen associated molecular patterns" that may affect microbial pathogenesis and anti-microbial responses. Additionally, bacteria produce metabolites, while viruses could change the metabolic profiles of the infected cells. Here, we used an unbiased metabolomics approach to profile metabolites in spleens and blood of murine leukemia virus-infected mice monocolonized with

Indexed as

Retroviridae InfectionsAnimalsBacteriaLeukemia Virus, MurineMetabolomicsMiceSpleencommensal bacteriametabolitesmicrobiotaretroviruses

Identifiers

PMID36851600
PMCPMC9967258
OpenAlexW4318478670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.