Evidence map›Paper›PMID 36851548›Full record

ArticleViruses2023

Detection of Hepatitis E Virus Genotype 3 in Feces of Capybaras (Hydrochoeris hydrochaeris) in Brazil.

Lia Cunha, Adriana Luchs, Lais S Azevedo, Vanessa C M Silva, Marcilio F Lemos, Antonio C Costa, Adriana P Compri, Yasmin França, Ellen Viana, Fernanda Malta and 7 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Lia CunhaInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Adriana LuchsInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.ORCID 0000-0003-4131-990X
Lais S AzevedoInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Vanessa C M SilvaInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Marcilio F LemosInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Antonio C CostaInstituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0001-5516-5177
Adriana P CompriInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Yasmin FrançaInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Ellen VianaInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Fernanda MaltaHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.
Roberta S MedeirosInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Raquel GuiducciInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Simone G MorilloInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.
Michele S Gomes-GouveaInstituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo 05403-000, Brazil.
Deyvid AmgartenHospital Israelita Albert Einstein, Sao Paulo 05652-900, Brazil.
João R R PinhoInstituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo 05403-000, Brazil.ORCID 0000-0003-3999-0489
Regina C MoreiraInstituto Adolfo Lutz, Sao Paulo 01246-902, Brazil.ORCID 0000-0002-8208-8776
Instituto Adolfo Lutz · BRUniversidade de São Paulo · BRHospital Israelita Albert Einstein · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis E virus (HEV) is an emerging zoonotic pathogen associated with relevant public health issues. The aim of this study was to investigate HEV presence in free-living capybaras inhabiting urban parks in São Paulo state, Brazil. Molecular characterization of HEV positive samples was undertaken to elucidate the genetic diversity of the virus in these animals. A total of 337 fecal samples were screened for HEV using RT-qPCR and further confirmed by conventional nested RT-PCR. HEV genotype and subtype were determined using Sanger and next-generation sequencing. HEV was detected in one specimen (0.3%) and assigned as HEV-3f. The IAL-HEV_921 HEV-3f strain showed a close relationship to European swine, wild boar and human strains (90.7-93.2% nt), suggesting an interspecies transmission. Molecular epidemiology of HEV is poorly investigated in Brazil; subtype 3f has been reported in swine. This is the first report of HEV detected in capybara stool samples worldwide.

Indexed as

Hepatitis E virusAnimalsBrazilFecesGenotypeHumansRodentiaSwinegenotype 3Hepatitis E virusphylogenypublic healthzoonosis

Identifiers

PMID36851548
PMCPMC9959927
OpenAlexW4317932546

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.