Evidence map›Paper›PMID 36851537›Full record

ArticleViruses2023

The Frequency and Function of NKG2C

Khlood Alsulami, Franck P Dupuy, Louise Gilbert, Marc Messier-Peet, Madeleine Durand, Cécile Tremblay, Jean-Pierre Routy, Julie Bruneau, Jean-Guy Baril, Benoit Trottier and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Khlood AlsulamiResearch Institute of the McGill University Health Centre (RI-MUHC), Glen Site, Bloc E, 1001 Decarie Blvd., Room EM3.3238, Montreal, QC H4A 3J1, Canada.
Franck P DupuyResearch Institute of the McGill University Health Centre (RI-MUHC), Glen Site, Bloc E, 1001 Decarie Blvd., Room EM3.3238, Montreal, QC H4A 3J1, Canada.
Louise GilbertResearch Institute of the McGill University Health Centre (RI-MUHC), Glen Site, Bloc E, 1001 Decarie Blvd., Room EM3.3238, Montreal, QC H4A 3J1, Canada.
Marc Messier-PeetCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Madeleine DurandCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Cécile TremblayCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Jean-Pierre RoutyResearch Institute of the McGill University Health Centre (RI-MUHC), Glen Site, Bloc E, 1001 Decarie Blvd., Room EM3.3238, Montreal, QC H4A 3J1, Canada.ORCID 0000-0001-9897-7589
Julie BruneauCentre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC H2X 0A9, Canada.
Jean-Guy BarilClinique de Médecine Urbaine du Quartier Latin, Montreal, QC H2L 4E9, Canada.
Benoit TrottierClinique de Médecine Urbaine du Quartier Latin, Montreal, QC H2L 4E9, Canada.
Nicole F BernardResearch Institute of the McGill University Health Centre (RI-MUHC), Glen Site, Bloc E, 1001 Decarie Blvd., Room EM3.3238, Montreal, QC H4A 3J1, Canada.ORCID 0000-0001-5311-9409
McGill University Health Centre · CACentre Hospitalier de l’Université de Montréal · CA

Funding

CIHR 148491CIHR CTN272CIHR HAL-157985CIHR TCO-125276
6 · The paper itself

Abstract

Human cytomegalovirus (CMV) infection drives the expansion and differentiation of natural killer (NK) cells with adaptive-like features. We investigated whether age and time on antiretroviral therapy (ART) influenced adaptive NK cell frequency and functionality. Flow cytometry was used to evaluate the frequency of adaptive and conventional NK cells in 229 CMV

Indexed as

CoinfectionCytomegalovirus InfectionsHIV InfectionsAgedAged, 80 and overCD57 AntigensHumansKiller Cells, NaturalNK Cell Lectin-Like Receptor Subfamily CTumor Necrosis Factor-alphaCD57 AntigensKLRC2 protein, humanNK Cell Lectin-Like Receptor Subfamily CTumor Necrosis Factor-alphaadaptive NK cellsagingCMVHIVNK cellspeople living with HIV (PLWH)

Identifiers

PMID36851537
PMCPMC9959045
OpenAlexW4317932637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.