Evidence map›Paper›PMID 36851501›Full record

ArticleViruses2023

Quinazolinone-Peptido-Nitrophenyl-Derivatives as Potential Inhibitors of SARS-CoV-2 Main Protease.

Huynh-Nguyet-Huong Giang, Feng-Pai Chou, Ching-Yun Chen, Shen-Chieh Chou, Sheng-Cih Huang, Tuoh Wu, Bui-Thi-Buu Hue, Hong-Cheu Lin, Tung-Kung Wu

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. A Novel Fluorescence Polarization Binding Assay for the Main Protease (MACS pharmacology & translational science · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Huynh-Nguyet-Huong GiangDepartment of Material Science, National Yang Ming Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan.
Feng-Pai ChouDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Ching-Yun ChenDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Shen-Chieh ChouDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.ORCID 0000-0002-7292-5905
Sheng-Cih HuangDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Tuoh WuDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Bui-Thi-Buu HueDepartment of Chemistry, College of Natural Sciences, Can Tho University, Can Tho City 721337, Vietnam.
Hong-Cheu LinDepartment of Material Science, National Yang Ming Chiao Tung University, 1001 Ta-Hsueh Rd., Hsinchu 30010, Taiwan.
Tung-Kung WuDepartment of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
National Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2-M

Indexed as

COVID-19Coronavirus 3C ProteasesGlutamic AcidHumansMolecular Docking SimulationSARS-CoV-23C-like proteinase, SARS-CoV-2Coronavirus 3C ProteasesGlutamic Acidmain protease MpropeptidomimeticquinazolinoneSARS-CoV-2targeted covalent inhibitor

Identifiers

PMID36851501
PMCPMC9963287
OpenAlexW4317517572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.