Evidence map›Paper›PMID 36851425›Full record

ArticleVeterinary sciences2023

Effect of Deferoxamine on Post-Transfusion Iron, Inflammation, and In Vitro Microbial Growth in a Canine Hemorrhagic Shock Model: A Randomized Controlled Blinded Pilot Study.

Melissa A Claus, Lisa Smart, Anthea L Raisis, Claire R Sharp, Sam Abraham, Joel P A Gummer, Martin K Mead, Damian L Bradley, Rachel Van Swelm, Erwin T G Wiegerinck and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinary sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Melissa A ClausSchool of Veterinary Medicine, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0003-1529-1480
Lisa SmartSchool of Veterinary Medicine, Murdoch University, Murdoch, WA 6150, Australia.
Anthea L RaisisSchool of Veterinary Medicine, Murdoch University, Murdoch, WA 6150, Australia.
Claire R SharpSchool of Veterinary Medicine, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0002-1797-9783
Sam AbrahamSchool of Veterinary Medicine, Murdoch University, Murdoch, WA 6150, Australia.ORCID 0000-0003-0950-2317
Joel P A GummerForensic Sciences Laboratory, ChemCentre, Resources and Chemistry Precinct, Bentley, WA 6102, Australia.
Martin K MeadSchool of Veterinary Medicine, Murdoch University, Murdoch, WA 6150, Australia.
Damian L BradleyIntensive Care Unit, Rockingham General Hospital, Cooloongup, WA 6168, Australia.
Rachel Van SwelmHepcidinanalysis.com, Department of Laboratory Medicine, Translational Metabolic Laboratory (TML 830), Radboud University Medical Center, 6525 Nijmegen, The Netherlands.
Erwin T G WiegerinckHepcidinanalysis.com, Department of Laboratory Medicine, Translational Metabolic Laboratory (TML 830), Radboud University Medical Center, 6525 Nijmegen, The Netherlands.
Edward LittonIntensive Care Unit, Fiona Stanley Hospital, Murdoch, WA 6150, Australia.ORCID 0000-0002-5125-6829
Murdoch University · AURadboud University Nijmegen · NLEdith Cowan University · AURockingham General HospitalThe University of Western Australia · AU

Funding

American College of Veterinary Emergency and Critical Care n/aIntensive Care Foundation of Australia and New Zealand n/aMetabolomics Australia, and the Murdoch University Research Training Program n/aMurdoch University Veterinary Life Science Small Grants n/a
6 · The paper itself

Abstract

Red blood cell (RBC) transfusion is associated with recipient inflammation and infection, which may be triggered by excessive circulating iron. Iron chelation following transfusion may reduce these risks. The aim of this study was to evaluate the effect of deferoxamine on circulating iron and inflammation biomarkers over time and in vitro growth of

Indexed as

chelationdesferrioxaminehepcidinlabile plasma ironnon-transferrin-bound ironstorage lesion

Identifiers

PMID36851425
PMCPMC9962370
OpenAlexW4319318299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.