Evidence map›Paper›PMID 36851353›Full record

ArticleVaccines2023

SARS-CoV-2 Infection-Blocking Immunity Post Natural Infection: The Role of Vitamin D.

Rami Abu Fanne, Mahmud Moed, Aviv Kedem, Ghalib Lidawi, Emad Maraga, Fady Mohsen, Ariel Roguin, Simcha-Ron Meisel

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Rami Abu FanneLeumit Health Services, Tel Aviv 6473817, Israel.
Mahmud MoedLeumit Health Services, Tel Aviv 6473817, Israel.
Aviv KedemLeumit Health Services, Tel Aviv 6473817, Israel.
Ghalib LidawiUrology Department, Hillel Yaffe Medical Center, Hadera 3810101, Israel.
Emad MaragaClinical Biochemistry Department, Hadassah Medical Center, Jerusalem 9103102, Israel.
Fady MohsenHeart Institute, Hillel Yaffe Medical Center, Hadera 3810101, Israel.
Ariel RoguinHeart Institute, Hillel Yaffe Medical Center, Hadera 3810101, Israel.
Simcha-Ron MeiselHeart Institute, Hillel Yaffe Medical Center, Hadera 3810101, Israel.
Hillel Yaffe Medical Center · ILClalit Health Services · ILHadassah Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

OBJECTIVE AND

aimThe extent of the protection against SARS-CoV-2 conferred by natural infection is unclear. Vitamin D may have a role in the interplay between SARS-CoV-2 infection and the evolving acquired immunity against it. We tested the correlation between baseline 25(OH) D content and both the reinfection rate and the anti-spike protein antibody titer following COVID-19 infection. Methods A retrospective observational survey that included a large convalescent COVID-19 population of subjects insured by the Leumit HMO was recorded between 1 February 2020 and 30 January 2022. Inclusion criteria required at least one available 25(OH)D level prior to enlistment. The association between 25(OH)D levels, the rate of breakthrough infection, and the anti-spike protein antibody titer was evaluated. Results A total of 10,132 COVID-19 convalescent subjects were included, of whom 322 (3.3%) sustained reinfection within a one-year follow-up. In the first 8 months after recovery, the reinfected patients were characterized by a higher incidence of low 25(OH)D levels (<30 ng/mL, 92% vs. 84.8%,

Indexed as

humoral responserecoveryreinfectionvitamin D

Identifiers

PMID36851353
PMCPMC9967845
OpenAlexW4321372890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.