Evidence map›Paper›PMID 36851302›Full record

ArticleVaccines2023

Investigation of Neurological Complications after COVID-19 Vaccination: Report of the Clinical Scenarios and Review of the Literature.

Wei-Ping Chen, Ming-Hua Chen, Shih-Ta Shang, Yung-Hsi Kao, Kuo-An Wu, Wen-Fang Chiang, Jenq-Shyong Chan, Hann-Yeh Shyu, Po-Jen Hsiao

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Post-COVID-19 Vaccination CNS Magnetic Resonance Imaging Findings: A Systematic Review.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Wei-Ping ChenDepartment of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.
Ming-Hua ChenDivision of Neurology, Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.
Shih-Ta ShangInfectious Disease, Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.
Yung-Hsi KaoDepartment of Life Sciences, National Central University, Taoyuan 320, Taiwan.
Kuo-An WuDivision of Pulmonary & Critical Care Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.
Wen-Fang ChiangDivision of Nephrology, Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.ORCID 0000-0002-5192-6706
Jenq-Shyong ChanDivision of Nephrology, Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.
Hann-Yeh ShyuDivision of Neurology, Department of Internal Medicine, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.
Po-Jen HsiaoDepartment of Life Sciences, National Central University, Taoyuan 320, Taiwan.ORCID 0000-0003-4965-0285
Taoyuan Armed Forces General Hospital · TWTri-Service General Hospital · TWNational Central University · TW

Funding

Taoyuan Armed Forces General Hospital, Taiwan TYAFGH-D-111038
6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in 2019 and became a pandemic in 2020. Since then, vaccines have been approved to prevent severe illness. However, vaccines are associated with the risk of neurological complications ranging from mild to severe. Severe complications such as vaccine-induced immune thrombotic thrombocytopenia (VITT) associated with acute ischaemic stroke have been reported as rare complications post-COVID-19 vaccination. During the pandemic era, VITT evaluation is needed in cases with a history of vaccination within the last month prior to the event. Cerebral venous sinus thrombosis (CVST) should be suspected in patients following immunization with persistent headaches who are unresponsive to analgesics. In this article, we investigated neurological complications after COVID-19 vaccination and provided more subsequent related clinical studies of accurate diagnosis, pathophysiological mechanisms, incidence, outcome, and management.

Indexed as

Bell’s palsycerebral venous sinus thrombosisCOVID-19 vaccinesGuillain—Barré syndromeneurological complicationspostvaccinal meningitis and encephalitistransverse myelitisvaccine-associated herpes simplex encephalitis

Identifiers

PMID36851302
PMCPMC9966113
OpenAlexW4320491696

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.