Evidence map›Paper›PMID 36851233›Full record

ArticleVaccines2023

One-Year Post-Vaccination Longitudinal Follow-Up of Quantitative SARS-CoV-2 Anti-Spike Total Antibodies in Health Care Professionals and Evaluation of Correlation with Surrogate Neutralization Test.

Yesim Tuyji Tok, Rabia Can Sarinoglu, Seyhan Ordekci, Serife Yilmaz, Gunes Ozcolpan, Aysen Bayram, Okan Kadir Nohut, Ipek Kocer, Ufuk Hasdemir, Mert Ahmet Kuskucu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Yesim Tuyji TokDepartment of Medical Microbiology, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, 34098 Istanbul, Turkey.ORCID 0000-0003-4970-9216
Rabia Can SarinogluDepartment of Medical Microbiology, Bahcesehir University Medical School, 34353 Istanbul, Turkey.
Seyhan OrdekciDepartment of Medical Microbiology, Ministry of Health University Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, 34303 Istanbul, Turkey.
Serife YilmazDepartment of Medical Microbiology, Karabuk University Medical School, 78100 Karabük, Turkey.ORCID 0000-0002-8002-092X
Gunes OzcolpanDepartment of Medical Microbiology, Aydın Adnan Menderes Medical School, 09100 Aydın, Turkey.
Aysen BayramDepartment of Medical Microbiology, SANKO University Medical School, 27090 Gaziantep, Turkey.ORCID 0000-0001-8232-628X
Okan Kadir NohutFikret Biyal Central Research Laboratory, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, 34098 Istanbul, Turkey.ORCID 0000-0002-8111-8072
Ipek KocerDepartment of Medical Microbiology, SANKO University Medical School, 27090 Gaziantep, Turkey.
Ufuk HasdemirDepartment of Medical Microbiology, Marmara University Pendik Training and Research Hospital, 34854 Istanbul, Turkey.
Mert Ahmet KuskucuDepartment of Medical Microbiology, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, 34098 Istanbul, Turkey.
Dildar KonukogluDepartment of Medical Biochemistry, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, 34098 Istanbul, Turkey.
Aysegul GozalanDepartment of Medical Microbiology, Alanya Alaaddin Keykubat Medical School, 07400 Alanya, Turkey.
Kenan MidilliDepartment of Medical Microbiology, Istanbul University-Cerrahpasa, Cerrahpasa Medical School, 34098 Istanbul, Turkey.
Gulden CelikDepartment of Medical Microbiology, Bahcesehir University Medical School, 34353 Istanbul, Turkey.
Istanbul University-Cerrahpaşa · TRBahçeşehir University · TRSanko University · TRAdnan Menderes University · TRAlanya University · TRKarabük University · TRMarmara University · TRMinistry of Health · TR

Funding

Bahçeşehir University BAUBAP.2021.01.21
6 · The paper itself

Abstract

Numerous vaccines have been generated to decrease the morbidity and mortality of COVID-19. This study aims to evaluate the immunogenicity of the heterologous boosts by BioNTech against homologous boosts by CoronaVac at three-month intervals in two health care worker (HCW) cohorts, with or without prior COVID-19, for one year post-vaccination. This is a prospective cohort study in which the humoral responses of 386 HCWs were followed-up longitudinally in six main groups according to their previous COVID-19 exposure and vaccination status. Anti-SARS-CoV-2 spike-RBD total antibody levels were measured and SARS-CoV-2 neutralization antibody (NAbs) responses against the ancestral Wuhan and the Omicron variant were evaluated comparatively using international standard serum for Wuhan and Omicron, as well as with the aid of a conversion tool. The anti-SARS-CoV-2 spike-RBD total Ab and Nab difference between with and without prior COVID-19, three months after two-dose primary vaccination with CoronaVac, was statistically significant (

Indexed as

COVID-19heterologousinactivatedmRNAvaccine

Identifiers

PMID36851233
PMCPMC9966239
OpenAlexW4319315944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.