Evidence map›Paper›PMID 36851143›Full record

ArticleVaccines2023

Risk Analysis Stratification of CIN 2+ Development in a Cohort of Women Living with HIV with Negative Pap Smear and HR-HPV Test during a Long-Term Follow-Up.

Barbara Gardella, Alberto Agarossi, Mattia Dominoni, Isabella Pagano, Susanna Del Frati, Maria Di Giminiani, Selene Cammarata, Chiara Melito, Marianna Francesca Pasquali, Lucia Zanchi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Two Multidrug-ResistantPathogens (Basel, Switzerland) · 2026
    Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Barbara GardellaDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-0812-8995
Alberto AgarossiDepartment of Obstetrics and Gynecology, L. Sacco Hospital, ASST-Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.ORCID 0000-0002-3872-8510
Mattia DominoniDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6322-607X
Isabella PaganoDepartment of Obstetrics and Gynecology, L. Sacco Hospital, ASST-Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.
Susanna Del FratiDepartment of Obstetrics and Gynecology, L. Sacco Hospital, ASST-Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.
Maria Di GiminianiDepartment of Obstetrics and Gynecology, L. Sacco Hospital, ASST-Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.ORCID 0000-0002-8211-0144
Selene CammarataDepartment of Obstetrics and Gynecology, L. Sacco Hospital, ASST-Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.
Chiara MelitoDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Marianna Francesca PasqualiDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3744-7888
Lucia ZanchiDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Valeria SavasiDepartment of Obstetrics and Gynecology, L. Sacco Hospital, ASST-Fatebenefratelli-Sacco, University of Milan, 20157 Milan, Italy.ORCID 0000-0002-1476-7689
Arsenio SpinilloDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.
University of Milan · ITUniversity of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWomen living with Human Immunodeficiency Virus are at higher risk of cervical cancer and precancer compared to women without HIV infection. The aim of the study is to evaluate the risk factors for the development of CIN2+ in a cohort of WLWH with negative colposcopy and cytology during a long follow-up period.

methodsWe enrolled, in a multicentric retrospective cohort study, WLWH who attended the colposcopic services from 1999 to 2019. Patients with a normal Pap smear, a negative HR-HPV test, and at least one year of follow-up were considered for the anlysis.

resultsThe five-year cumulative incidence of histologically confirmed HSIL was 8.3% (95% CI = 2.6-13.6) among subjects with a CD4+ cell count of <200 cells/µL at any visit and 2.1% (95% CI = 0.7-3.4,

conclusionsWLWH with good immune status and negative Pap smear and HR-HPV test have a low risk for CIN2+.

Indexed as

cervical intraepithelial neoplasiacolposcopyhuman immunodeficiency virushuman papillomavirus

Identifiers

PMID36851143
PMCPMC9961029
OpenAlexW4318204048

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.