Evidence map›Paper›PMID 36850993›Full record

ReviewToxics2023

A Review of Common Cyanotoxins and Their Effects on Fish.

Halina Falfushynska, Nadiia Kasianchuk, Eduard Siemens, Eliana Henao, Piotr Rzymski

Open access · goldAbstract readReview
In one paragraph

Review in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
9.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 68 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 3 countries.

Halina FalfushynskaDepartment of Marine Biology, Institute for Biological Sciences, University of Rostock, 18059 Rostock, Germany.ORCID 0000-0003-3058-4919
Nadiia KasianchukFaculty of Biology, Adam Mickiewicz University, 61712 Poznan, Poland.ORCID 0000-0002-9732-329X
Eduard SiemensFaculty of Electrical, Mechanical and Industrial Engineering, Anhalt University for Applied Sciences, 06366 Köthen, Germany.
Eliana HenaoResearch Group Integrated Management of Ecosystems and Biodiversity XIUÂ, School of Biological Sciences, Universidad Pedagógica y Tecnológica de Colombia, Tunja 150003, Colombia.ORCID 0000-0003-3449-3010
Piotr RzymskiDepartment of Environmental Medicine, Poznan University of Medical Sciences, 61701 Poznan, Poland.ORCID 0000-0002-4713-0801
Anhalt University of Applied Sciences · DEAdam Mickiewicz University in Poznań · PLPedagogical and Technological University of Colombia · COPoznan University of Medical Sciences · PL

Funding

Alexander von Humboldt Foundation Personal grant to HF
6 · The paper itself

Abstract

Global warming and human-induced eutrophication drive the occurrence of various cyanotoxins in aquatic environments. These metabolites reveal diversified mechanisms of action, encompassing cyto-, neuro-, hepato-, nephro-, and neurotoxicity, and pose a threat to aquatic biota and human health. In the present paper, we review data on the occurrence of the most studied cyanotoxins, microcystins, nodularins, cylindrospermopsin, anatoxins, and saxitoxins, in the aquatic environment, as well as their potential bioaccumulation and toxicity in fish. Microcystins are the most studied among all known cyanotoxins, although other toxic cyanobacterial metabolites are also commonly identified in aquatic environments and can reveal high toxicity in fish. Except for primary toxicity signs, cyanotoxins adversely affect the antioxidant system and anti-/pro-oxidant balance. Cyanotoxins also negatively impact the mitochondrial and endoplasmic reticulum by increasing intracellular reactive oxygen species. Furthermore, fish exposed to microcystins and cylindrospermopsin exhibit various immunomodulatory, inflammatory, and endocrine responses. Even though cyanotoxins exert a complex pressure on fish, numerous aspects are yet to be the subject of in-depth investigation. Metabolites other than microcystins should be studied more thoroughly to understand the long-term effects in fish and provide a robust background for monitoring and management actions.

Indexed as

aquatic environmentcyanobacteriaecotoxicologytoxin bioaccumulation

Identifiers

PMID36850993
PMCPMC9961407
OpenAlexW4318053958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.