Evidence map›Paper›PMID 36850582›Full record

ArticleSensors (Basel, Switzerland)2023

Identification of a Gait Pattern for Detecting Mild Cognitive Impairment in Parkinson's Disease.

Michela Russo, Marianna Amboni, Paolo Barone, Maria Teresa Pellecchia, Maria Romano, Carlo Ricciardi, Francesco Amato

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michela RussoDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, 80125 Naples, Italy.
Marianna AmboniDepartment of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84081 Baronissi, Italy.
Paolo BaroneDepartment of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84081 Baronissi, Italy.
Maria Teresa PellecchiaDepartment of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84081 Baronissi, Italy.
Maria RomanoDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, 80125 Naples, Italy.
Carlo RicciardiDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, 80125 Naples, Italy.ORCID 0000-0001-7290-6432
Francesco AmatoDepartment of Electrical Engineering and Information Technology, University of Naples Federico II, 80125 Naples, Italy.ORCID 0000-0002-9053-3139

Funding

University of Salerno FARB2019
6 · The paper itself

Abstract

The aim of this study was to determine a gait pattern, i.e., a subset of spatial and temporal parameters, through a supervised machine learning (ML) approach, which could be used to reliably distinguish Parkinson's Disease (PD) patients with and without mild cognitive impairment (MCI). Thus, 80 PD patients underwent gait analysis and spatial-temporal parameters were acquired in three different conditions (normal gait, motor dual task and cognitive dual task). Statistical analysis was performed to investigate the data and, then, five ML algorithms and the wrapper method were implemented: Decision Tree (DT), Random Forest (RF), Naïve Bayes (NB), Support Vector Machine (SVM) and K-Nearest Neighbour (KNN). First, the algorithms for classifying PD patients with MCI were trained and validated on an internal dataset (sixty patients) and, then, the performance was tested by using an external dataset (twenty patients). Specificity, sensitivity, precision, accuracy and area under the receiver operating characteristic curve were calculated. SVM and RF showed the best performance and detected MCI with an accuracy of over 80.0%. The key features emerging from this study are stance phase, mean velocity, step length and cycle length; moreover, the major number of features selected by the wrapper belonged to the cognitive dual task, thus, supporting the close relationship between gait dysfunction and MCI in PD.

Indexed as

Cognitive DysfunctionParkinson DiseaseBayes TheoremGaitGait AnalysisHumansgait analysismachine learningmild cognitive impairmentParkinson’s disease

Identifiers

PMID36850582
PMCPMC9963713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.