Evidence map›Paper›PMID 36850271›Full record

ArticlePolymers2023

Antimicrobial Formulation of a Bacterial Nanocellulose/Propolis-Containing Photosensitizer for Biomedical Applications.

Isabella Salgado Gonçalves, Lais Roncalho Lima, Andresa Aparecida Berretta, Nathaly Alcazar Amorim, Sebastião Pratavieira, Thaila Quatrini Corrêa, Flávia Aparecida Resende Nogueira, Hernane Silva Barud

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Applications of propolis-based materials in wound healing.Archives of dermatological research · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Isabella Salgado GonçalvesLaboratório de Biopolímeros e Biomateriais-BioPolMat, University of Araraquara, Araraquara 14801-320, SP, Brazil.ORCID 0000-0002-0873-5787
Lais Roncalho LimaChemistry Department, Federal University of São Carlos, São Carlos 13565-905, SP, Brazil.ORCID 0000-0002-2159-6320
Andresa Aparecida BerrettaResearch, Development and Innovation Department, Apis Flora Indl. Coml. Ribeirão, Preto 14020-670, SP, Brazil.ORCID 0000-0001-5719-1301
Nathaly Alcazar AmorimResearch, Development and Innovation Department, Apis Flora Indl. Coml. Ribeirão, Preto 14020-670, SP, Brazil.
Sebastião PratavieiraPhysics Institute of São Carlos, University of São Paulo, São Carlos 05508-060, SP, Brazil.ORCID 0000-0002-5012-8470
Thaila Quatrini CorrêaPhysics Institute of São Carlos, University of São Paulo, São Carlos 05508-060, SP, Brazil.ORCID 0000-0002-2527-1451
Flávia Aparecida Resende NogueiraLaboratório de Biopolímeros e Biomateriais-BioPolMat, University of Araraquara, Araraquara 14801-320, SP, Brazil.ORCID 0000-0002-9432-5919
Hernane Silva BarudLaboratório de Biopolímeros e Biomateriais-BioPolMat, University of Araraquara, Araraquara 14801-320, SP, Brazil.
Universidade Federal de São Carlos · BRApis Flora (Brazil) · BRCentro Universitário de Araraquara · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Institutos Nacionais de Ciência e Tecnologia 2013/07793-6Institutos Nacionais de Ciência e Tecnologia 2014/50857 8Institutos Nacionais de Ciência e Tecnologia 2017/16278-9National Council for Scientific and Technological Development 306919/2019-2National Council for Scientific and Technological Development 407822/2018-6National Council for Scientific and Technological Development 465360/2014-9São Paulo Research Foundation 2009/54035-4São Paulo Research Foundation 2013/07276 1
6 · The paper itself

Abstract

With the aim of contributing to the development of more efficient materials for wound care, new topical formulations based on bacterial nanocellulose (BNC) hydrogels containing propolis were produced. Characterizations confirmed the incorporation of propolis into the BNC matrix, maintaining its structure and properties. Rheological analysis confirmed that the hydrogels showed thixotropic behavior appropriate for topical application. Chromatographic profiles showed sustained release of propolis biomarkers for at least 20 h. The formulations did not present mutagenicity. For application in photodynamic inactivation (PDI), BNC/propolis hydrogels were prepared with the photosensitizers methylene blue (MB). Spectroscopy and confocal fluorescence microscopy confirmed the interaction of MB and propolis in BNC hydrogels, as well as the formation of a new composite material. In the antibacterial assays, formulations containing MB and propolis significantly reduced

Indexed as

antimicrobialbacterial nanocellulosehydrogelsphotodynamic inactivationpropoliswound healing

Identifiers

PMID36850271
PMCPMC9968145
OpenAlexW4321107750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.