ArticlePolymers2023
Design, Synthesis, and Characterization of Novel Bis-Uracil Chitosan Hydrogels Modified with Zinc Oxide Nanoparticles for Boosting Their Antimicrobial Activity.
Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 33 citations in OpenAlex.
- Efficient adsorption of fast green dye by chitosan modified with cyanoguanidine: statistical modelling, kinetic, and isotherm studies.BMC chemistry · 2026Article
- Adsorption of Ciprofloxacin onto CMCs/XG Hydrogel: Optimization, Kinetic, and Isotherm Studies.Polymers · 2026Article
- Novel xanthan gum hydrogels boosted with crosslinked carboxymethyl chitosan and zinc oxide nanoparticles: synthesis, characterization and biological activity evaluation.BMC chemistry · 2025Article
- Article
- Chitosan and Its Nanoparticles: A Multifaceted Approach to Antibacterial Applications.Nanomaterials (Basel, Switzerland) · 2025Review
- Hydrogel Containing Propolis: Physical Characterization and Evaluation of Biological Activities for Potential Use in the Treatment of Skin Lesions.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Antibacterial Hydrogels for Wound Dressing Applications: Current Status, Progress, Challenges, and Trends.Gels (Basel, Switzerland) · 2024Review
- Antimicrobial Properties of Chitosan-Modified Cotton Fabric Treated with Aldehydes and Zinc Oxide Particles.Materials (Basel, Switzerland) · 2023Article
- Green nanocoating-based polysaccharides decorated with ZnONPs doped Egyptian kaolinite for antimicrobial coating paper.Scientific reports · 2023Article
- Polyaniline-Coated Surface-Modified Ag/PANI Nanostructures for Antibacterial and Colorimetric Melamine Sensing in Milk Samples.ACS omega · 2023Article
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new series of hydrogels was successfully prepared by incorporating various substituted bisuracil (R-BU) linkages between chitosan Schiff's base chains (R-BU-CsSB) and between chitosan chains (R-BU-Cs). After protection of the amino groups of chitosan by benzaldehyde, yielding chitosan Schiff's base (CsSB), the reaction with epichlorohydrin was confined on the -OH on C6 to produce epoxy chitosan Schiff's base (ECsSB), which was reacted with R-BU to form R-BU-CsSB hydrogels, and finally, the bioactive amino groups of chitosan were restored to obtain R-BU-Cs hydrogels. Further, some R-BU-Cs-based ZnO nanoparticle (R-BU-Cs/ZnONPs) composites were also prepared. Appropriate techniques such as elemental analysis, FTIR, XRD, SEM, and EDX were used to verify their structures. Their inhibition potency against all the tested microbes were arranged as: ZnONPs bio-composites > R-BU-Cs hydrogels > R-BU-CsSB hydrogels > Cs. Their inhibition performance against Gram-positive bacteria was better than Gram-negative ones. Their minimum inhibitory concentration (MIC) values decreased as a function of the negative resonance effect of the substituents in the aryl ring of R-BU linkages in the hydrogels. Compared with
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Registered trials
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