Evidence map›Paper›PMID 36849948›Full record

ArticleBMC psychiatry2023

'Just snap out of it' - the experience of loneliness in women with perinatal depression: a Meta-synthesis of qualitative studies.

Katherine Adlington, Cristina Vasquez, Eiluned Pearce, Claire A Wilson, Rebecca Nowland, Billie Lever Taylor, Sarah Spring, Sonia Johnson

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07223736 (Postpartum Education Via Artificial Intelligence for Recovery and Loneliness), which is not on this map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07223736 narecruitingnot on this mapstarted 2026, after this paper: background citation

Postpartum Education Via Artificial Intelligence for Recovery and Loneliness (PEARL): A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, San DiegoRan2026 to 2026Enrolled130ConditionsPelvic Floor Disorder, Loneliness, Postpartum, Mental HealthArmsGenerative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

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  5. Perceived connectedness during the perinatal period: Implications for parent and child well-being.Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43) · 2026
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  18. Engage & connect psychotherapy improves social reward responsivity and reduces postpartum depression.Psychotherapy research : journal of the Society for Psychotherapy Research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Katherine AdlingtonDivision of Psychiatry, University College London, London, UK. katherine.adlington@nhs.net.ORCID 0000-0002-9296-4952
Cristina VasquezDivision of Psychiatry, University College London, London, UK.ORCID 0000-0001-9171-2879
Eiluned PearceDivision of Psychiatry, University College London, London, UK.ORCID 0000-0002-4347-317X
Claire A WilsonSection of Women's Mental Health, King's College London, London, UK.ORCID 0000-0003-2169-5115
Rebecca NowlandSchool of Health and Midwifery, University of Central Lancashire, Preston, UK.ORCID 0000-0003-4326-2425
Billie Lever TaylorSection of Women's Mental Health, King's College London, London, UK.ORCID 0000-0002-6865-3425
Sarah SpringPerson with lived experience, London, UK.
Sonia JohnsonDivision of Psychiatry, University College London, London, UK.ORCID 0000-0002-2219-1384
University College London · GBKing's College London · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Lancashire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnancy and the arrival of a new baby is a time of great transition and upheaval. Women often experience social isolation and loneliness at this time and may develop depression, particularly in the postnatal period. Qualitative studies have reported that loneliness is also a feature of perinatal depression. However, until now there has been no attempt to synthesise research exploring the links between loneliness and perinatal depression. This study's aim was to explore existing qualitative evidence to answer two research questions: What are the experiences of loneliness for women with perinatal depression? What helps and what makes loneliness worse for women with perinatal depression?

methodsA qualitative meta-synthesis retrieved primary qualitative studies relevant to the research questions. Four electronic databases were systematically searched (Ovid MEDLINE®; PsycINFO; Embase; Web of Science). Papers were screened according to pre-defined inclusion criteria and assigned a quality score. Thematic analysis was used to identify major overarching themes in the literature.

resultsTwenty-seven relevant qualitative studies were included. Themes relating to the interaction between perinatal depression and loneliness included self-isolation and hiding symptoms due to stigma of perinatal depression and fear of judgement as a 'bad mother'; a sudden sense of emotional disconnection after birth; and a mismatch between expected and actual support provided by partner, family and community. There was also a double burden of loneliness for women from disadvantaged communities, due to increased stigma and decreased social support. Validation and understanding from healthcare professionals, peer support from other mothers with experience of perinatal depression, and practical and emotional family support were all important factors that could ameliorate loneliness.

conclusionsLoneliness appears to play a central role in the experience of perinatal depression based on the frequency with which it emerged in women's accounts. The findings provide a foundation for the development of further theories about the role of loneliness in perinatal depression and evidence in which future psychological and social intervention design processes can be rooted. Addressing stigma and offering culturally appropriate professional and peer support are potential targets for interventions that could help women with perinatal depression, particularly in disadvantaged communities, feel less lonely.

trial registrationProspero registration: https://www.crd.york.ac.uk/prospero/display_record.php? RecordID = 251,936.

Indexed as

Depressive DisorderLonelinessDepressionEmotionsFemaleHumansInfantPregnancySocial IsolationAntenatal depressionLonelinessPerinatal depressionPostnatal depressionPostpartum depressionQualitative metasynthesisQualitative synthesis

Identifiers

PMID36849948
PMCPMC9970854
OpenAlexW4322485664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.