Evidence map›Paper›PMID 36849827›Full record

ArticleEye (London, England)2023

The effect of sex and laterality on the phenotype of primary rhegmatogenous retinal detachment.

Mariantonia Ferrara, Anna Song, Mohaimen Al-Zubaidy, Peter Avery, D Alistair Laidlaw, Tom H Williamson, David Yorston, David H W Steel, BEAVRS Retinal Detachment Outcomes Group

Open access · hybridAbstract read
In one paragraph

Article in Eye (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Preoperative Retinal Detachment Variables Causing Macular Detachment.Clinical ophthalmology (Auckland, N.Z.) · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 20 institutions in 5 countries.

Mariantonia Ferrara *Newcastle Eye Centre, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, NE1 4PL, UK.ORCID 0000-0002-1191-4989
Anna Song *Biosciences Institute, Newcastle University, Catherine Cookson Building, Newcastle upon Tyne, NE2 4HH, UK.ORCID 0000-0002-9852-1124
Mohaimen Al-ZubaidyBiosciences Institute, Newcastle University, Catherine Cookson Building, Newcastle upon Tyne, NE2 4HH, UK.
Peter AverySchool of Mathematics & Statistics, Newcastle University, Herschel Building, Newcastle Upon Tyne, NE1 7RU, UK.
D Alistair LaidlawGuy's and St. Thomas' NHS Foundation Trust, New City Court 20 St. Thomas Street, London, SE1 9RT, UK.
Tom H WilliamsonGuy's and St. Thomas' NHS Foundation Trust, New City Court 20 St. Thomas Street, London, SE1 9RT, UK.ORCID 0000-0002-1879-449X
David YorstonGartnavel Hospital, 1053 Great Western Road, Glasgow, G12 0YN, UK.ORCID 0000-0001-7259-5320
David H W SteelBiosciences Institute, Newcastle University, Catherine Cookson Building, Newcastle upon Tyne, NE2 4HH, UK. David.steel@ncl.ac.uk.ORCID 0000-0001-8734-3089
BEAVRS Retinal Detachment Outcomes Group
Sunderland Eye Infirmary · GBManchester Royal Eye Hospital · GBRoyal Hallamshire Hospital · GBGartnavel General Hospital · GBGuy's and St Thomas' NHS Foundation Trust · GBMusgrove Park Hospital · GBNewcastle University · GBNew Cross Hospital · GBPrincess Alexandra Eye Pavilion · GBRadboud University Nijmegen · NLRoyal Bournemouth Hospital · GBRoyal Victoria Infirmary · GBUniversity of Hull · GBCumberland Infirmary · GBEast Suffolk and North Essex NHS Foundation Trust · GBFondation de Rothschild · FRHull and East Yorkshire Hospitals NHS Trust · GBInstituto Cajal · ESJames Paget University Hospital · GBMaidstone and Tunbridge Wells NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the effect of sex and laterality on clinical features of primary rhegmatogenous retinal detachment (RRD).

methodThis study is a retrospective analysis of data prospectively collected. We extracted data from two online datasets over a 7-year period of patients older than 16 years who had undergone surgery for primary RRD. Data on baseline characteristics were analyzed to compare males versus females, and right versus left eyes.

resultsOf 8133 eyes analyzed, 4342 (53.4%) were right. The overall male predominance (63.7%) was more marked in the age range 50-69 years. Men were more commonly pseudophakic and presented more frequently with baseline posterior vitreous detachment (PVD). Female sex was significantly associated with baseline myopia, retinal holes as causative retinal break, and isolated inferior RD. Men had more frequent foveal involvement, greater RRD extent, greater numbers and larger sized retinal tears including dialysis and giant retinal tears. Regarding laterality, foveal involvement, larger retinal breaks, isolated temporal RD and temporal retinal breaks were more common in right eyes, whereas left eyes were more myopic at baseline and presented more frequently with isolated nasal RD and nasal retinal breaks.

conclusionsThis study confirmed the predominance of male sex and right laterality in RRD. Sex and laterality were associated with multiple presenting features of RRD including extent, break distribution, number, size and type, as well as RD distribution.

Indexed as

MyopiaRetinal DetachmentRetinal PerforationsAgedFemaleFovea CentralisHumansMaleMiddle AgedPhenotypeRetrospective StudiesVitrectomy

Identifiers

PMID36849827
PMCPMC10517129
OpenAlexW4322495796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.