Evidence map›Paper›PMID 36849730›Full record

ArticleCommunications biology2023

Evaluating elimination thresholds and stopping criteria for interventions against the vector-borne macroparasitic disease, lymphatic filariasis, using mathematical modelling.

Swarnali Sharma, Morgan E Smith, Shakir Bilal, Edwin Michael

Abstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Swarnali SharmaChristian Medical College, IDA Scudder Road, Vellore, Tamil Nadu, 632004, India. swarnali.sharma87@gmail.com.ORCID 0000-0003-0903-5974
Morgan E SmithDepartment of Biological Sciences, University of Notre Dame, Notre Dame, South Bend, IN, USA.
Shakir BilalCenter for Global Health Infectious Disease Research, University of South Florida, Tampa, FL, USA.ORCID 0000-0003-4425-0805
Edwin MichaelCenter for Global Health Infectious Disease Research, University of South Florida, Tampa, FL, USA. emichael443@usf.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We leveraged the ability of EPIFIL transmission models fit to field data to evaluate the use of the WHO Transmission Assessment Survey (TAS) for supporting Lymphatic Filariasis (LF) intervention stopping decisions. Our results indicate that understanding the underlying parasite extinction dynamics, particularly the protracted transient dynamics involved in shifts to the extinct state, is crucial for understanding the impacts of using TAS for determining the achievement of LF elimination. These findings warn that employing stopping criteria set for operational purposes, as employed in the TAS strategy, without a full consideration of the dynamics of extinction could seriously undermine the goal of achieving global LF elimination.

Indexed as

Elephantiasis, FilarialModels, TheoreticalHumans

Identifiers

PMID36849730
PMCPMC9971242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.