Evidence map›Paper›PMID 36849414›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2023

Andrew R McKinstry-Wu, Andrzej Z Wasilczuk, William P Dailey, Roderic G Eckenhoff, Max B Kelz

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrew R McKinstry-WuDepartment of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Philadelphia 19104.
Andrzej Z WasilczukDepartment of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Philadelphia 19104.ORCID 0000-0002-1492-2319
William P DaileyDepartment of Chemistry, University of Pennsylvania School of Arts and Sciences, Philadelphia, Pennsylvania 19104.
Roderic G EckenhoffDepartment of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Philadelphia 19104.
Max B KelzDepartment of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, Philadelphia 19104 kelzma@pennmedicine.upenn.edu.ORCID 0000-0002-2803-6078
University of Pennsylvania · USUniversity of the Sciences · US

Funding

Training Program in Neuroengineering and MedicineT32NS091006 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Brian Litt · 2015 to 2026
$4.1M
NEURONAL BASIS UNDERLYING VOLATILE ANESTHETIC INDUCED HYPNOSISR01GM088156 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI KELZ, MAX · 2010 to 2021
$3.8M
Personalized Anesthesia: The Role of the Locus Coeruleus in Individual Anesthetic ResponsesR35GM142712 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MCKINSTRY-WU, ANDREW RICH · 2021 to 2025
$2.2M
OptoanesthesiaR01GM107117 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI KELZ, MAX · 2014 to 2017
$1.3M
Intersections of Sleep and Coma: Neural Pathways of Alpha-2 Adrenergic HypnosisK08GM123317 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MCKINSTRY-WU, ANDREW RICH · 2017 to 2021
$877k
NIGMS NIH HHS K08 GM123317NIGMS NIH HHS R01 GM088156NIGMS NIH HHS R01 GM107117NIGMS NIH HHS R35 GM142712NINDS NIH HHS T32 NS091006
6 · The paper itself

Abstract

Photoaffinity ligands are best known as tools used to identify the specific binding sites of drugs to their molecular targets. However, photoaffinity ligands have the potential to further define critical neuroanatomic targets of drug action. In the brains of WT male mice, we demonstrate the feasibility of using photoaffinity ligands

Indexed as

Anesthetics, IntravenousBrainHypnosisHypnotics and SedativesLigandsPhotoaffinity LabelsPropofolAdrenergic NeuronsAnesthesia, IntravenousAnimalsDiazomethaneElectrocorticographyElectroencephalographyLocus CoeruleusMaleMice2-isopropyl-5-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenolAnesthetics, IntravenousDiazomethaneHypnotics and SedativesLigandsPhotoaffinity LabelsPropofolanesthesiahypnosislocus coeruleusneuronal mechanismsphoto affinity ligandsedation

Identifiers

PMID36849414
PMCPMC10072292
OpenAlexW4322490195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.