Evidence map›Paper›PMID 36848875›Full record

ArticleAdvanced healthcare materials2023

Incorporating Tantalum Oxide Nanoparticles into Implantable Polymeric Biomedical Devices for Radiological Monitoring.

Kendell M Pawelec, Ethan Tu, Shatadru Chakravarty, Jeremy M L Hix, Lane Buchanan, Legend Kenney, Foster Buchanan, Nandini Chatterjee, Subhashri Das, Adam Alessio and 1 more

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  15. X-Ray Visible Protein Scaffolds by Bulk Iodination.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  16. Biomaterials for Drug Delivery and Human Applications.Materials (Basel, Switzerland) · 2024
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Kendell M PawelecDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.ORCID 0000-0003-2606-4136
Ethan TuDepartment of Biomedical Engineering, Michigan State University, 775 Woodlot Dr, East Lansing, MI, 48824, USA.
Shatadru ChakravartyDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.ORCID 0000-0003-0855-318X
Jeremy M L HixDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.ORCID 0000-0002-9593-787X
Lane BuchananDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.
Legend KenneyDepartment of Biomedical Engineering, Michigan State University, 775 Woodlot Dr, East Lansing, MI, 48824, USA.
Foster BuchananDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.
Nandini ChatterjeeDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.
Subhashri DasDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.
Adam AlessioDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.
Erik M ShapiroDepartment of Radiology, Michigan State University, 846 Service Rd, East Lansing, MI, 48824, USA.ORCID 0000-0002-0901-5781

Funding

Radiopaque 3D printed tissue engineered scaffolds for nerve generationR01EB029418 · NIBIB · MICHIGAN STATE UNIVERSITY · PI Erik Shapiro · 2021 to 2026
$3.2M
NIBIB NIH HHS R01 EB029418
6 · The paper itself

Abstract

Longitudinal radiological monitoring of biomedical devices is increasingly important, driven by the risk of device failure following implantation. Polymeric devices are poorly visualized with clinical imaging, hampering efforts to use diagnostic imaging to predict failure and enable intervention. Introducing nanoparticle contrast agents into polymers is a potential method for creating radiopaque materials that can be monitored via computed tomography. However, the properties of composites may be altered with nanoparticle addition, jeopardizing device functionality. Thus, the material and biomechanical responses of model nanoparticle-doped biomedical devices (phantoms), created from 0-40 wt% tantalum oxide (TaO

Indexed as

NanoparticlesOxidesPolymersTantalumTomography, X-Ray ComputedOxidesPolymersTantalumtantalum oxidecomputed tomographydegradationmonitoringnanoparticlesradiopacity

Identifiers

PMID36848875
PMCPMC10460461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.