ArticleJournal of critical care2023
Recovery after AKI: Effects on outcomes over 15 years.
Article in Journal of critical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Long-term risks of adverse kidney outcomes after acute kidney injury: a systematic review and meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Pooled it
- Acute kidney injury at a tertiary nephrology referral center: predictors of renal recovery and in-hospital mortality.BMC nephrology · 2026Observational
- Organelle Crosstalk in Renal Cells: Insights from Cell Biology and Implications for AKI-to-CKD Transition.International journal of molecular sciences · 2026Review
- Community-Acquired Acute Kidney Injury in Central India: Etiology, Clinical Profile, and In-Hospital Outcomes.Cureus · 2026Article
- Development of a Clinical Prediction Model for Acute Kidney Injury Among In-Hospital Cardiac Arrest Patients During Intensive Care Unit Hospitalization.Reviews in cardiovascular medicine · 2026Article
- Deep learning approaches for time series prediction of renal recovery in medical critically Ill patients with acute kidney injury: LSTM, GRU, and transformer models.Critical care (London, England) · 2026Article
- What is Outpatient AKI? Insights from the SPRINT AKI Cohort.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Postoperative acute kidney injury and serum creatinine: still central, still limited.Acute and critical care · 2026Article
- Why interventions to prevent acute kidney injury are needed now and why preventing long-term outcomes will only come later.Intensive care medicine · 2025Article
- Dexmedetomidine and acute kidney injury in patients with sepsis: a retrospective cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- Development and validation of a prediction model for 90-day mortality among critically ill patients with AKI undergoing CRRT.Journal of nephrology · 2025Article
- Persistent severe acute kidney injury is a major modifiable determinant of outcome during critical illness.Intensive care medicine · 2025Article
- Identification of ALDH2 as a novel target for the treatment of acute kidney injury in kidney transplantation based on WGCNA and machine learning algorithms and exploration of its potential mechanism of action using animal experiments.Frontiers in immunology · 2025Article
- Renal recovery after acute kidney injury requiring dialysis: Predictors and long-term outcomes.Qatar medical journal · 2025Article
- Investigating an appropriate indicator of acute kidney injury for patient prognosis following lung transplantation.Renal failure · 2024Article
- Outcome and Determining Characteristics of ICU Patients with Acute Kidney Injury in a Low-Income Country, a Multicenter Experience.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024Article
- Biomarkers in acute kidney injury.Annals of intensive care · 2024Review
- Association between serum osmolality and deteriorating renal function in patients with acute myocardial infarction: analysis of the MIMIC- IV database.BMC cardiovascular disorders · 2024Article
- Pre-existing chronic kidney disease, aetiology of acute kidney injury and infection do not affect renal outcome and mortality.Journal of nephrology · 2024Article
- An early warning model to predict acute kidney injury in sepsis patients with prior hypertension.Heliyon · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeTo examine the effect of kidney recovery on mortality, dialysis and kidney transplantation up to 15 years after AKI. MATERIALS AND
methodsWe studied 29,726 survivors of critical illness and compared these outcomes stratified by AKI and recovery status at hospital discharge. Kidney recovery was defined as a return of serum creatinine to ≤150% of baseline without dialysis prior to hospital discharge.
resultsOverall AKI occurred in 59.2% in which two thirds developed stage 2-3 AKI. Recovery rate of AKI at hospital discharge was 80.8%. Patients who did not recover experienced the worst 15-year mortality compared to those who recovered and those without AKI (57.8% vs 45.2% vs 30.3%, p < 0.001). This pattern was also found in subgroups of patients with suspected sepsis-associated (57.1% vs 47.9% vs 36.5%, p < 0.001) and cardiac surgery-associated AKI (60.1% vs 41.8% vs 25.9%, p < 0.001). The rates of dialysis and transplantation at 15 years were low and not associated with recovery status.
conclusionsRecovery of AKI in critically ill patients at hospital discharge had an effect on long-term mortality for up to 15 years. These results have implications for acute care, follow-up and choice of endpoints for clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.