Evidence map›Paper›PMID 36848649›Full record

ArticlePLoS biology2023

Exclusion of latecomers yields a patchwork of viral subpopulations within hosts.

Anice C Lowen, Lucas M Ferreri

Abstract readComment
In one paragraph

Article in PLoS biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Anice C LowenDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.ORCID 0000-0002-9829-112X
Lucas M FerreriDepartment of Microbiology and Immunology, Emory University School of Medicine, Atlanta, Georgia, United States of America.

Funding

Host dependence of influenza A virus spatio-temporal dynamicsR01AI127799 · NIAID · EMORY UNIVERSITY · PI Anice C Lowen · 2017 to 2026
$4.5M
Role of spatial structure in shaping viral population diversity and evolutionR01AI154894 · NIAID · EMORY UNIVERSITY · PI KOELLE, KATHARINA V, LOWEN, ANICE C · 2020 to 2024
$2.8M
NIAID NIH HHS R01 AI127799NIAID NIH HHS R01 AI154894
6 · The paper itself

Abstract

Viruses arriving late to an individual cell are blocked from replicating, an effect called superinfection exclusion. A study in PLOS Biology indicates that this exclusion at the level of individual cells gives rise to a heterogenous landscape of infection within a host.

Indexed as

OrthomyxoviridaeSuperinfectionHumans

Identifiers

PMID36848649
PMCPMC9910647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.