Evidence map›Paper›PMID 36848201›Full record

ArticleThe British journal of surgery2023

Implementation and validation of a novel instrument for the grading of unexpected events in paediatric surgery: Clavien-Madadi classification.

Omid Madadi-Sanjani, Joachim F Kuebler, Julia Brendel, Soeren Wiesner, Annika Mutanen, Simon Eaton, Anja Domenghino, Pierre-Alain Clavien, Benno M Ure

Open access · hybridAbstract read
In one paragraph

Article in The British journal of surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 54 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 5 countries.

Omid Madadi-SanjaniDepartment of Pediatric Surgery, Hannover Medical School, Hannover, Germany.
Joachim F KueblerDepartment of Pediatric Surgery, Hannover Medical School, Hannover, Germany.
Julia BrendelDepartment of Pediatric Surgery, Hannover Medical School, Hannover, Germany.
Soeren WiesnerInstitute of Biostatistics, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-3989-8650
Annika MutanenEuropean Reference Network for Rare Inherited and Congenital Anomalies (ERNICA).
Simon EatonEuropean Reference Network for Rare Inherited and Congenital Anomalies (ERNICA).ORCID 0000-0003-0892-9204
Anja DomenghinoDepartment of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-8617-409X
Pierre-Alain ClavienDepartment of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-9916-7905
Benno M UreDepartment of Pediatric Surgery, Hannover Medical School, Hannover, Germany.
Medizinische Hochschule Hannover · DEUniversity Hospital of Zurich · CHGreat Ormond Street Hospital · GBUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInconsistent definitions of complications and unexpected events have limited accurate analysis of surgical outcomes. Perioperative outcome classifications currently used for adult patients have limitations when used for children.

methodsA multidisciplinary group of experts modified the Clavien-Dindo classification to increase its utility and accuracy in paediatric surgery cohorts. Organizational and management errors were considered in the novel Clavien-Madadi classification, which focuses on procedural invasiveness rather than anaesthetic management. Unexpected events were prospectively documented in a paediatric surgery cohort. Results of the Clavien-Dindo and Clavien-Madadi classifications were compared and correlated with procedure complexity.

resultsUnexpected events were prospectively documented in a cohort of 17 502 children undergoing surgery between 2017 and 2021. The results of both classifications were highly correlated (ρ = 0.95), although the novel Clavien-Madadi classification identified 449 additional events (organizational and management errors) over the Clavien-Dindo classification, increasing the total number of events by 38 per cent (1605 versus 1158 events). The results of the novel system correlated significantly with the complexity of procedures in children (ρ = 0.756). Furthermore, grading of events > grade III according to the Clavien-Madadi classification showed a higher correlation with procedure complexity (ρ = 0.658) than the Clavien-Dindo classification (ρ = 0.198).

conclusionThe Clavien-Madadi classification is a tool for the detection of surgical and non-medical errors in paediatric surgery populations. Further validation in paediatric surgery populations is required before widespread use.

Indexed as

Postoperative ComplicationsSurgical Procedures, OperativeChildHumansPediatrics

Identifiers

PMID36848201
PMCPMC10364500
OpenAlexW4322486468

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.