SynthesisCurrent environmental health reports2023
A Systematic Review of the Placental Translocation of Micro- and Nanoplastics.
Synthesis in Current environmental health reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Micro and Nanoplastics and Obstetric Outcomes in Humans and Animals: A Systematic Review.International journal of environmental research and public health · 2026Pooled it
- Private, public, and bottled drinking water: Shared contaminant-mixture exposures and effects challenge.Environment international · 2025Pooled it
- Polystyrene nanoplastics disrupt mouse placenta development in a sex-dependent manner.Reproductive toxicology (Elmsford, N.Y.) · 2026Article
- Micro- and nanoplastics in pediatric health: from placental transfer to neurodevelopmental outcomes.Pediatric research · 2026Review
- Microplastics in the umbilical vein of fetal growth restricted and healthy fetuses: A preliminary Turkish selected case series.Turkish journal of obstetrics and gynecology · 2026Article
- Microplastics in the Female Genital Tract and Fetoplacental Continuum: A Lesion-Based Framework for Pathophysiological Interpretation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Review
- Article
- Tracking of [Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Polystyrene Nanoplastics Disrupt Mouse Placenta Development in a Sex-Dependent Manner.bioRxiv : the preprint server for biology · 2026Article
- Early Life Microplastic Exposure Impairs Mouse Incisor Enamel Formation.Calcified tissue international · 2026Article
- Parental polystyrene nanoplastics exposure increases susceptibility to pathogen infection in offspring via H3K36me3-UPRCell communication and signaling : CCS · 2026Article
- Emerging cardiovascular risks of micro- and nanoplastics: toxic effects and mechanistic pathways.Particle and fibre toxicology · 2026Review
- Micro- and nanoplastics as environmental modifiers of neuroimmune dysfunction in Parkinson's disease.Frontiers in neuroscience · 2026Review
- Replacement bisphenols, phthalates, and micro-/nanoplastic exposures in human reproductive endocrinology.Frontiers in endocrinology · 2026Review
- Environmental Micro-Nanoplastics and Musculoskeletal Disorders: Current Research and Insights.International journal of nanomedicine · 2026Review
- Microplastics and child health: A scoping review of prenatal and early-life exposure routes and potential health risks.Toxicology reports · 2025Review
- Micro- and Nanoplastics in Dentistry: Challenges in Obtaining High-Quality Evidence.Materials (Basel, Switzerland) · 2025Review
- Microplastics: A threat to Fetoplacental unit and Reproductive systems.Toxicology reports · 2025Review
- Micro- and Nanoplastics and Fetal Health: Challenges in Assessment and Evidence from Epidemiological Studies.Toxics · 2025Review
- Microplastics and probiotics: Mechanisms of interaction and their consequences for health.AIMS microbiology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purpose of reviewDespite increasing awareness of the ubiquity of microplastics (MPs) in our environments, little is known about their risk of developmental toxicity. Even less is known about the environmental distribution and associated toxicity of nanoplastics (NPs). Here, we review the current literature on the capacity for MPs and NPs to be transported across the placental barrier and the potential to exert toxicity on the developing fetus. RECENT
findingsThis review includes 11 research articles covering in vitro, in vivo, and ex vivo models, and observational studies. The current literature confirms the placental translocation of MPs and NPs, depending on physicochemical properties such as size, charge, and chemical modification as well as protein corona formation. Specific transport mechanisms for translocation remain unclear. There is emerging evidence of placental and fetal toxicity due to plastic particles based on animal and in vitro studies. Nine out of eleven studies examined in this review found that plastic particles were capable of placental translocation. In the future, more studies are needed to confirm and quantify the existence of MPs and NPs in human placentas. Additionally, translocation of different plastic particle types and heterogenous mixtures across the placenta, exposure at different periods of gestation, and associations with adverse birth and other developmental outcomes should also be investigated.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.