Evidence map›Paper›PMID 36847984›Full record

ArticleApplied biochemistry and biotechnology2023

Green Synthesis of Silver Nanoparticles Using Salvadora persica and Caccinia macranthera Extracts: Cytotoxicity Analysis and Antimicrobial Activity Against Antibiotic-Resistant Bacteria.

Roshanak Khojasteh-Taheri, Ahmad Ghasemi, Zahra Meshkat, Zahra Sabouri, Mahnaz Mohtashami, Majid Darroudi

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Article in Applied biochemistry and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
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  11. A comprehensive review on potential applications of metallic nanoparticles as antifungal therapies to combat human fungal diseases.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Review
  12. Article
  13. Article
  14. Green synthesis of selenium nanoparticles usingAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Roshanak Khojasteh-TaheriAntimicrobial Resistance Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Ahmad GhasemiHealthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran.
Zahra MeshkatAntimicrobial Resistance Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Zahra SabouriApplied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahnaz MohtashamiDepartment of Microbiology, Neyshabur Islamic Azad University of Sciences, Neyshabur, Iran. mahnazmohtashami@iau-neyshabur.ac.ir.
Majid DarroudiDepartment of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran. darroudim@mums.ac.ir.
Mashhad University of Medical Sciences · IRUniversity of Neyshabur · IRIslamic Azad University, Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Silver nanoparticles (AgNPs) have gained great interest because of their specific and distinct properties. Chemically synthesized AgNPs (cAgNPs) are often unsuitable for medical applications due to requiring toxic and hazardous solvents. Thus, green synthesis of AgNPs (gAgNPs) using safe and nontoxic substances has attracted particular focus. The current study investigated the potential of Salvadora persica and Caccinia macranthera extracts in the synthesis of CmNPs and SpNPs, respectively. Aqueous extracts of Salvadora persica and Caccinia macranthera were prepared and taken as reducing and stabilizing agents through gAgNPs synthesis. The antimicrobial effects of gAgNPs against susceptible and antibiotic-resistant bacterial strains and their toxicity effects on L929 fibroblast normal cells were evaluated. TEM images and particle size distribution analysis showed that the CmNPs and SpNPs have average sizes of 14.8 nm and 39.4 nm, respectively. The XRD confirms the crystalline nature and purity of both CmNPs and SpNPs. FTIR results demonstrate the involvement of the biologically active substances of both plant extracts in the green synthesis of AgNPs. According to MIC and MBC results, higher antimicrobial effects were seen for CmNPs with a smaller size than SpNPs. In addition, CmNPs and SpNPs were much less cytotoxic when examined against a normal cell relative to cAgNPs. Based on high efficacy in controlling antibiotic-resistant pathogens without detrimental adverse effects, CmNPs may have the capacity to be used in medicine as imaging, drug carrier, and antibacterial and anticancer agents.

Indexed as

Metal NanoparticlesSalvadoraceaeAnti-Bacterial AgentsBacteriaGreen Chemistry TechnologyMicrobial Sensitivity TestsPlant ExtractsSilverSpectroscopy, Fourier Transform InfraredAnti-Bacterial AgentsPlant ExtractsSilverAntibiotic-resistant bacteriaAntimicrobial effectCaccinia macrantheraCytotoxicityGreen synthesisSalvadora persicaSilver nanoparticles

Identifiers

PMID36847984
OpenAlexW4322495823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.