Evidence map›Paper›PMID 36847894›Full record

Trial reportJournal of autism and developmental disorders2024

Examining the Relationship Between Anxiety Severity and Autism-Related Challenges During Cognitive Behavioral Therapy for Children with Autism.

Madeleine N Fuselier, Andrew G Guzick, Jafar Bakhshaie, Jeffrey J Wood, Philip C Kendall, Connor M Kerns, Brent J Small, Wayne K Goodman, Eric A Storch

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Madeleine N FuselierDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Blvd, Suite 4-400, Houston, TX 77030, USA.
Andrew G GuzickDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Blvd, Suite 4-400, Houston, TX 77030, USA.
Jafar BakhshaieDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Jeffrey J WoodDepartment of Education, University of California, Los Angeles, Los Angeles, CA, USA.
Philip C KendallDepartment of Psychology, Temple University, Philadelphia, PA, USA.
Connor M KernsDepartment of Psychology, University of British Columbia, Vancouver, BC, Canada.
Brent J SmallSchool of Aging Studies, University of South Florida, Tampa, FL, USA.
Wayne K GoodmanDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Blvd, Suite 4-400, Houston, TX 77030, USA.
Eric A StorchDepartment of Psychiatry and Behavioral Sciences, Baylor College of Medicine, 1977 Butler Blvd, Suite 4-400, Houston, TX 77030, USA. eric.storch@bcm.edu.ORCID http://orcid.org/0000-0002-7631-3703
Baylor College of Medicine · USCalifornia Department of Education · USMassachusetts General Hospital · USTemple University · USUniversity of British Columbia · CAUniversity of South Florida · US

Funding

Preclinical and Clincial OutcomesP50HD103555 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MIRJANA MALETIC-SAVATIC · 2020 to 2026
$9.9M
Web-based mind-body treatment to enhance resilience among patients with painful nontraumatic upper extremity conditions and comorbid risky substance useK23AT012364 · NCCIH · MASSACHUSETTS GENERAL HOSPITAL · PI Jafar Bakhshaie · 2023 to 2026
$681k
1/3 Treatment of Anxiety in Autism Spectrum DisorderR01HD080098 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOOD, JEFFREY JAMES · 2014 to 2016
$663k
2/3 Treatment of Anxiety in Autism Spectrum DisorderR01HD080096 · NICHD · UNIVERSITY OF SOUTH FLORIDA · PI STORCH, ERIC A. · 2014 to 2016
$471k
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5P50HD103555Eunice Kennedy Shriver National Institute of Child Health and Human Development HD080096NCCIH NIH HHS K23 AT012364NICHD NIH HHS P50 HD103555NICHD NIH HHS R01 HD080096NICHD NIH HHS R01 HD080098The National Institute of Child Health and Human Development R01-HD080098
6 · The paper itself

Abstract

purposeUsing data from a randomized clinical trial evaluating cognitive behavioral therapy (CBT) for children with autism and co-occurring anxiety, this study examined the relationship between autism features and anxiety symptoms throughout CBT.

methodsTwo multilevel mediation analyses were run which examined the mediating role of changes in anxiety for changes in two core features of autism, (a) repetitive and restrictive behaviors (RRBs) and (b) social communication/interaction impairments, between pre- and post-treatment.

resultsIndirect effects between time and autism characteristics were significant for both models, indicating that as anxiety changes, so do RRBs and social communication/interaction as the outcomes respectively.

conclusionFindings suggest a bidirectional relationship between anxiety and autism features. Implications of these findings are discussed.

Indexed as

AnxietyAutistic DisorderCognitive Behavioral TherapyAutism Spectrum DisorderChildChild, PreschoolFemaleHumansMaleSeverity of Illness IndexSocial InteractionTreatment OutcomeAnxietyAssessmentAutism spectrum disorderCognitive behavioral therapyObsessive-compulsive disorderTreatment

Identifiers

PMID36847894
PMCPMC11846066
OpenAlexW4322494218

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.