Evidence map›Paper›PMID 36847868›Full record

SynthesisInternational journal of colorectal disease2023

Conservative surgery versus colorectal resection for endometriosis with rectal involvement: a systematic review and meta-analysis of surgical and long-term outcomes.

Luke O'Brien, Stefan Morarasu, Bianca Codrina Morarasu, Paul C Neary, Ana Maria Musina, Natalia Velenciuc, Cristian Ene Roata, Mihail Gabriel Dimofte, Sorinel Lunca, Diego Raimondo and 3 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Inverse association between obesity and intestinal endometriosis: Findings from a cross-sectional study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Observational
  3. Article
  4. Review
  5. Article
  6. Review
  7. Observational
  8. Minimally invasive surgery for deep endometriosis.Obstetrics & gynecology science · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Luke O'BrienDepartment of Colorectal Surgery, Tallaght University Hospital, Dublin 24, Ireland.
Stefan MorarasuDepartment of Colorectal Surgery, Tallaght University Hospital, Dublin 24, Ireland. morarasu.stefan@gmail.com.
Bianca Codrina MorarasuGrigore T Popa, University of Medicine and Pharmacy, Iasi, Romania.
Paul C NearyDepartment of Colorectal Surgery, Tallaght University Hospital, Dublin 24, Ireland.
Ana Maria Musina2nd Department of Surgical Oncology, Regional Institute of Oncology, Iasi, Romania.
Natalia Velenciuc2nd Department of Surgical Oncology, Regional Institute of Oncology, Iasi, Romania.
Cristian Ene Roata2nd Department of Surgical Oncology, Regional Institute of Oncology, Iasi, Romania.
Mihail Gabriel Dimofte2nd Department of Surgical Oncology, Regional Institute of Oncology, Iasi, Romania.
Sorinel Lunca2nd Department of Surgical Oncology, Regional Institute of Oncology, Iasi, Romania.
Diego RaimondoDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Renato SeracchioliDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Paolo CasadioDivision of Gynaecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Cillian ClancyDepartment of Colorectal Surgery, Tallaght University Hospital, Dublin 24, Ireland.
Institutul Regional de Oncologie · ROAzienda USL di Bologna · ITGrigore T. Popa University of Medicine and Pharmacy · ROTallaght University Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe optimal surgical approach for removal of colorectal endometrial deposits is unclear. Shaving and discoid excision of colorectal deposits allow organ preservation but risk recurrence with associated functional issues and re-operation. Formal resection risks potential higher complications but may be associated with lower recurrence rates. This meta-analysis compares peri-operative and long-term outcomes between conservative surgery (shaving and disc excision) versus formal colorectal resection.

methodsThe study was registered with PROSPERO. A systematic search was performed on PubMed and EMBASE databases. All comparative studies examining surgical outcomes in patients that underwent conservative surgery versus colorectal resection for rectal endometrial deposits were included. The two main groups (conservative versus resection) were compared in three main blocks of variables including group comparability, operative outcomes and long-term outcomes.

resultsSeventeen studies including 2861 patients were analysed with patients subdivided by procedure: colorectal resection (n = 1389), shaving (n = 703) and discoid excision (n = 742). When formal colorectal resection was compared to conservative surgery there was lower risk of recurrence (p = 0.002), comparable functional outcomes (minor LARS, p = 0.30, major LARS, p = 0.54), similar rates of postoperative leaks (p = 0.22), pelvic abscesses (p = 0.18) and rectovaginal fistula (p = 0.92). On subgroup analysis, shaving had the highest recurrence rate (p = 0.0007), however a lower rate of stoma formation (p < 0.00001) and rectal stenosis (p = 0.01). Discoid excision and formal resection were comparable.

conclusionColorectal resection has a significantly lower recurrence rate compared to shaving. There is no difference in complications or functional outcomes between discoid excision and formal resection and both have similar recurrence rates.

Indexed as

Abdominal AbscessColorectal NeoplasmsEndometriosisFemaleHumansRectovaginal FistulaReoperationColorectal surgeryEndometriosisMeta-analysisSurgerySurgery outcomes

Identifiers

PMID36847868
OpenAlexW4322496345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.