Evidence map›Paper›PMID 36847814›Full record

ArticleWorld journal of urology2023

Intraoperative complication of radical cystectomy for muscle-invasive bladder cancer: does the surgical approach matter? A retrospective multicenter study using the EAUiaiC classification.

Igor Duquesne, Daniel Benamran, Alexandra Masson-Lecomte, Alexandre De La Taille, Michael Peyromaure, Morgan Rouprêt, Nicolas Barry Delongchamps

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Igor DuquesneDepartment of Urology, APHP, Cochin Hospital, Paris Cité Université, 75014, Paris, France. igor.duquesne@aphp.fr.ORCID http://orcid.org/0000-0002-6716-6473
Daniel BenamranDepartement of Urology, Geneva University Hospitals, Geneva, Switzerland.
Alexandra Masson-LecomteDepartment of Urology, APHP, Saint Louis Hospital, Paris Cité University, 75010, Paris, France.
Alexandre De La TailleDepartment of Urology, APHP, Mondor Hospital, Paris Est Créteil University, 94000, Créteil, France.
Michael PeyromaureDepartment of Urology, APHP, Cochin Hospital, Paris Cité Université, 75014, Paris, France.
Morgan RouprêtDepartment of Urology, APHP, Pitié-Salpêtrière Hospital, Sorbonne University, 75013, Paris, France.
Nicolas Barry DelongchampsDepartment of Urology, APHP, Cochin Hospital, Paris Cité Université, 75014, Paris, France.
Université Paris Cité · FRSorbonne Université · FRUniversité Paris-Est Créteil · FRUniversity Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite surgical and anesthetic progress, radical cystectomy for bladder cancer remains one of the most morbid surgeries in urology. The objective of our study was to describe intraoperative complications and to assess the impact of surgical approach on morbidity.

methodsWe retrospectively reviewed medical records of patients treated by radical cystectomy for localized muscle invasive bladder cancer between 2015 and 2020, following the Martin et al. criteria for complications reports. All intraoperative adverse events were graded according to the EAUiaiC scores. Multivariate regression models were used to determine predicting factors of complications.

resultsA total of 318 patients were included for analysis. Among them, 17 patients (5.4%) presented an intraoperative complication. No preoperative oncological or clinical factor was associated with the occurrence of an intraoperative complication. Surgical approach had no impact on morbidity. Both overall survival (HR 2.02; CI95% 0.87-4.68; p = 0.101) and recurrence-free survival (HR 1.856; CI95% 0.804-4.284; p = 0.147) were not associated with intraoperative complication.

conclusionRadical cystectomy remains a highly morbid surgery and surgical approach did not improve the complication rate. Perioperative morbidity has a significant impact on patient survival. The association between intraoperative and postoperative complications illustrates the cumulative effect of perioperative events that are associated with survival.

Indexed as

CystectomyUrinary Bladder NeoplasmsHumansMusclesPostoperative ComplicationsRetrospective StudiesUrinary BladderBladder cancerComplicationsMorbidityRadical cystectomyUrothelial carcinoma

Identifiers

PMID36847814
OpenAlexW4322494612

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.