Evidence map›Paper›PMID 36847813›Full record

SynthesisWorld journal of urology2023

Occupational asbestos exposure and urinary bladder cancer: a systematic review and meta-analysis.

Nicolò Franco, Alessandro Godono, Marco Clari, Catalina Ciocan, Carlotta Zunarelli, Enrico Pira, Paolo Boffetta

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Bladder cancer risk factors: a comprehensive umbrella review of meta-analyses.International journal of surgery (London, England) · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Nicolò FrancoDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy.
Alessandro GodonoDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy.
Marco ClariDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy. marco.clari@unito.it.ORCID http://orcid.org/0000-0001-5927-2973
Catalina CiocanDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy.
Carlotta ZunarelliDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Enrico PiraDepartment of Public Health and Pediatrics, University of Torino, Turin, Italy.
Paolo BoffettaDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
University of Turin · ITDepartment of Public Health · USStony Brook University · USUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is conflicting evidence on the association between asbestos exposure and bladder cancer. We performed a systematic review and meta-analysis to provide evidence on occupational asbestos exposure and the risk of mortality and incidence of bladder cancer.

methodsWe searched three relevant electronic databases (Pubmed, Scopus, and Embase) from inception to October 2021. The methodological quality of included articles was evaluated using the US National Institutes of Health tool. Standardized incidence ratios (SIRs) and standardized mortality ratios (SMRs) for bladder cancer, as well as respective 95% confidence intervals (CIs), were extracted or calculated for each included cohort. Main and subgroup meta-analyses according to first year of employment, industry, sex, asbestos type, and geographic region were performed.

resultsFifty-nine publications comprising 60 cohorts were included. Bladder cancer incidence and mortality were not significantly associated with occupational asbestos exposure (pooled SIR: 1.04, 95% CI: 0.95-1.13, P = 0.000; pooled SMR: 1.06, 95% CI: 0.96-1.17, P = 0.031). Bladder cancer incidence was higher among workers employed between 1908 and 1940 (SIR: 1.15, 95% CI: 1.01-1.31). Mortality was elevated in asbestos workers cohorts (SMR: 1.12, 95% CI: 1.06-1.30) and in the subgroup analysis for women (SMR: 1.83, 95% CI: 1.22-2.75). No association was found between asbestos types and bladder cancer incidence or mortality. We observed no difference in the subgroup analysis for countries and no direct publication bias evidence.

conclusionThere is evidence that workers with occupational asbestos exposure have a bladder cancer incidence and mortality similar to the general population.

Indexed as

AsbestosLung NeoplasmsOccupational DiseasesOccupational ExposureUrinary Bladder NeoplasmsFemaleHumansIncidenceAsbestosAsbestosOccupational healthSystematic reviewUrinary bladder cancer

Identifiers

PMID36847813
PMCPMC10159975
OpenAlexW4322496483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.