Evidence map›Paper›PMID 36847619›Full record

ArticleTurkish journal of ophthalmology2023

Improvement of Prostaglandin-Associated Periorbitopathy after Discontinuing Treatment.

Jose Manuel Abalo-Lojo, Pedro Vázquez Ferreiro, Maria Knight Asorey, Aida Estévez Colmenero, Francisco Gonzalez

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Oculoplastic Challenges in Patients with Glaucoma.Turkish journal of ophthalmology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jose Manuel Abalo-LojoHospital Complex of the University of Santiago de Compostela, Department of Ophthalmology and Health Research Institute (IDIS), Santiago de Compostela, Spain.ORCID 0000-0002-4922-190X
Pedro Vázquez FerreiroHospital Virxe da Xunqueira, Ophthalmology Clinic, A Coruña, Spain.ORCID 0000-0001-8367-3996
Maria Knight AsoreyHospital Complex of the University of Santiago de Compostela, Department of Ophthalmology and Health Research Institute (IDIS), Santiago de Compostela, Spain.ORCID 0000-0001-8897-8174
Aida Estévez ColmeneroHospital Complex of the University of Santiago de Compostela, Department of Ophthalmology and Health Research Institute (IDIS), Santiago de Compostela, Spain.ORCID 0000-0002-5352-8808
Francisco GonzalezUniversity of Santiago de Compostela, Department of Surgery and Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Santiago de Compostela, Spain.ORCID 0000-0002-1461-5474
Universidade de Santiago de Compostela · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To report that the periorbital changes induced by prostaglandin analogue (PGA) eye drops are partially reversible after discontinuing treatment. Materials and Methods: Nine patients with prostaglandin-associated periorbitopathy seen in a referral oculoplastic practice were included in this study, eight with unilateral glaucoma and one with bilateral open-angle glaucoma. All of them had been treated with topical PGA for at least one year, before the treatment was discontinued for cosmetic reasons. Results: In all cases, there were evident periocular differences between the treated eye and the fellow eye, consisting mainly of deepening of the upper eyelid sulcus and eyelid fat pad reduction. One year after discontinuing the PGA eye drops, improvement of these features was observed. Conclusion: Clinicians and patients should be aware of the side effects of topical PGA therapy on periorbital tissues, and that these side effects can partially regress after discontinuation of the medication.

Indexed as

GlaucomaGlaucoma, Open-AngleEyelidsHumansOphthalmic SolutionsProstaglandinsOphthalmic SolutionsProstaglandinsperiorbital changesPeriorbitopathyprostaglandin analogueprostaglandin-associated periorbitopathy

Identifiers

PMID36847619
PMCPMC9973213
OpenAlexW4322496107

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.