ArticleObesity (Silver Spring, Md.)2023
Sleep duration and timing are prospectively linked with insulin resistance during late adolescence.
Article in Obesity (Silver Spring, Md.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Association between late bedtime and obesity in children and adolescents: a meta-analysis.Frontiers in pediatrics · 2024Pooled it
- Circadian gene expression in adolescents: Associations with concurrent circadian disruption and subsequent changes in cardiometabolic risk measures.Sleep medicine · 2026Article
- The role of parenting in associations of weight status with sleep duration and timing for children with mild sleep-disordered breathing.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Knowledge, Attitudes, and Practices Regarding Hyperuricemia and Sleep Among Patients: A Cross-Sectional Study.Patient preference and adherence · 2026Article
- Beyond metabolism: nutrition, sleep, and psychological wellbeing in children with insulin resistance-a case-control study.Frontiers in nutrition · 2026Article
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- Article
- Associations of a metal mixture and vitamin D with sleep duration among adolescents and young adults from the 2011-2018 NHANES cycles.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2025Article
- Metabolic syndrome in children and adolescents: definitions, epidemiology, pathophysiology, interventions, and challenges.Frontiers in endocrinology · 2025Review
- Weight-neutral approach and later sleep midpoint in adolescents with "emerging polycystic ovary syndrome phenotype" as vehicles for sustainable weight loss.F&S reports · 2024Article
- Review
- Wake up! It's time to recognize the importance of sleep in metabolic health.Obesity (Silver Spring, Md.) · 2023Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
objectiveThe aim of this study was to evaluate whether short sleep duration or later sleep timing is a risk factor for insulin resistance (IR) in late adolescence.
methodsMexico City adolescents enrolled in a longitudinal birth cohort (ELEMENT) took part in two study visits during peri-puberty that occurred approximately 2 years apart. IR was assessed with serum glucose and insulin. Four groups were defined using puberty-specific cut points: no IR over the follow-up period, transition from normal to IR, transition from IR to normal, and IR at both time points. Baseline sleep assessments were measured with 7-day wrist actigraphy. Multinomial logistic regression models were used to evaluate associations between sleep duration and timing with homeostatic model assessment of insulin resistance categories, adjusting for age, sex, and baseline pubertal status.
resultsAdolescents who were ≥ 1 hour below the sleep duration recommendations-for-age were 2.74 times more likely to develop IR (95% CI: 1.0-7.4). Similarly, adolescents who were in the latest category of sleep midpoint (>4:33 a.m.) were more likely than those with earliest midpoints (1 a.m.-3 a.m.) to develop IR (odds ratio = 2.63, 95% CI: 1.0-6.7). Changes in adiposity over follow-up did not mediate sleep and IR.
conclusionsInsufficient sleep duration and late sleep timing were associated with development of IR over a 2-year period in late adolescence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.