Evidence map›Paper›PMID 36847278›Full record

Trial reportThe British journal of nutrition2023

Habitual consumption of high-fibre bread fortified with bean hulls increased plasma indole-3-propionic concentration and decreased putrescine and deoxycholic acid faecal concentrations in healthy volunteers.

Marietta Sayegh, Qian Qian Ni, Viren Ranawana, Vassilios Raikos, Nicholas J Hayward, Helen E Hayes, Gary Duncan, Louise Cantlay, Freda Farquharson, Michael Solvang and 6 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The British journal of nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marietta SayeghThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.ORCID 0000-0002-2966-3786
Qian Qian NiThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Viren Ranawana *The Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Vassilios Raikos *The Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Nicholas J HaywardThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Helen E HayesThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.ORCID 0000-0001-5186-2696
Gary DuncanThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Louise CantlayThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Freda FarquharsonThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Michael SolvangThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Graham W HorganThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.ORCID 0000-0002-6048-1374
Petra LouisThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Wendy R RussellThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Miriam CleggInstitute for Food, Nutrition and Health and Department of Food and Nutritional Sciences, University of Reading, Whiteknights, UK.
Frank ThiesThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.
Madalina NeacsuThe Rowett Institute, University of Aberdeen, AberdeenAB25 2ZD, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Only 6 to 8 % of the UK adults meet the daily recommendation for dietary fibre. Fava bean processing lead to vast amounts of high-fibre by-products such as hulls. Bean hull fortified bread was formulated to increase and diversify dietary fibre while reducing waste. This study assessed the bean hull: suitability as a source of dietary fibre; the systemic and microbial metabolism of its components and postprandial events following bean hull bread rolls. Nine healthy participants (53·9 ± 16·7 years) were recruited for a randomised controlled crossover study attending two 3 days intervention sessions, involving the consumption of two bread rolls per day (control or bean hull rolls). Blood and faecal samples were collected before and after each session and analysed for systemic and microbial metabolites of bread roll components using targeted LC-MS/MS and GC analysis. Satiety, gut hormones, glucose, insulin and gastric emptying biomarkers were also measured. Two bean hull rolls provided over 85 % of the daily recommendation for dietary fibre; but despite being a rich source of plant metabolites (

Indexed as

FabaceaeGastrointestinal HormonesAdultBlood GlucoseBreadChromatography, LiquidCross-Over StudiesDeoxycholic AcidDietary FiberHealthy VolunteersHumansPutrescineTandem Mass SpectrometryBlood GlucoseDeoxycholic AcidDietary FiberGastrointestinal HormonesPutrescineAgricultural by-productsBean hullsDietary fibreFood fortificationHigh-fibre breadIndole 3-propionic acid

Identifiers

PMID36847278
PMCPMC10551484

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.