Evidence map›Paper›PMID 36846735›Full record

ArticleResearch in pharmaceutical sciences2023

Effects of GABA

Elahe Amohashemi, Hojjatallah Alaei, Parham Reisi

Abstract read
In one paragraph

Article in Research in pharmaceutical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elahe AmohashemiDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, I.R. Iran.
Hojjatallah AlaeiDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, I.R. Iran.
Parham ReisiDepartment of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, I.R. Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: The lateral habenula (LHb), a key area in the regulation of the reward system, exerts a major influence on midbrain neurons. It has been shown that the gamma-aminobutyric acid (GABA)- ergic system plays the main role in morphine dependency. The role of GABA type B receptors (GABA Experimental approach: The baseline firing rate was recorded for 15 min, then morphine (5 mg/kg; s.c) and phaclofen (0, 0.5, 1, and 2 μg/rat), a GABA Findings/Results: The results revealed that morphine decreased neuronal activity, and GABA Conclusion and implications: This result indicated that GABA

Indexed as

Extracellular single-unit recordingGABAB receptorsLateral habenulaMorphine

Identifiers

PMID36846735
PMCPMC9951782

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.