Evidence map›Paper›PMID 36846563›Full record

ArticleOxford open immunology2022

Molecular mimicry among human proteinase 3 and bacterial antigens: implications for development of c-ANCA associated vasculitis.

Y Chavez, J Garces, R Díaz, M Escobar, A Sanchez, E Buendía, M Múnera

Erratum issuedAbstract read
In one paragraph

Article in Oxford open immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Molecular Mimicry BetweenInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Y ChavezMedical Research Group (GINUMED) Universitary Corporation Rafael Nuñez, Centro Calle de la Soledad No. 5-70, Cartagena 130002, Colombia.
J GarcesMedical Research Group (GINUMED) Universitary Corporation Rafael Nuñez, Centro Calle de la Soledad No. 5-70, Cartagena 130002, Colombia.
R DíazMedical Research Group (GINUMED) Universitary Corporation Rafael Nuñez, Centro Calle de la Soledad No. 5-70, Cartagena 130002, Colombia.
M EscobarCatholic University of Manizales, Manizales, Av. Santander #No. 60, Manizales, Caldas 111321, Colombia.
A SanchezMedical Research Group (GINUMED) Universitary Corporation Rafael Nuñez, Centro Calle de la Soledad No. 5-70, Cartagena 130002, Colombia.
E BuendíaFaculty of Medicine, University of Cartagena, Cra. 50 #24120, Zaragocilla, Cartagena de Indias, Provincia de Cartagena, Bolívar, Cartagena 130014, Colombia.
M MúneraMedical Research Group (GINUMED) Universitary Corporation Rafael Nuñez, Centro Calle de la Soledad No. 5-70, Cartagena 130002, Colombia.ORCID https://orcid.org/0000-0003-3428-0541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wegener's granulomatosis is an autoimmune disease where autoantibodies target human autoantigen PR3, a serine protease locates on the neutrophil membrane. This disease affects blood small vessels and could be deadly. The origin of these autoantibodies is unknown, but infections have been implicated with autoimmune disease. In this study, we explored potential molecular mimicry between human PR3 and homologous pathogens through

Indexed as

autoantigenautoimmunitycross-reactivitymicrobialmolecular mimicryPR3

Identifiers

PMID36846563
PMCPMC9914470

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.