Evidence map›Paper›PMID 36846400›Full record

ArticleLaryngoscope investigative otolaryngology2023

Factors affecting adherence to intranasal treatment for allergic rhinitis: A qualitative study.

Meha G Fox, Lauren M Cass, Kevin J Sykes, Emily L Cummings, Scott N Fassas, Rohit Nallani, Josh B Smith, Alexander G Chiu, Jennifer A Villwock

Registry-linked trialAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07270302 (Safety and Efficacy of Nebulized Nasal Steroids for the Treatment of Chronic Rhinosinusitis), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07270302 phase1 / phase2not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Safety and Efficacy of Nebulized Nasal Steroids for the Treatment of Chronic Rhinosinusitis

TypeinterventionalSponsorWashington University School of MedicineRan2025 to 2026Enrolled50ConditionsChronic RhinosinusitisArmsnebulized budesonide via NasoNeb, budesonide lavage via NeilMed
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Meha G FoxDepartment of Otolaryngology - Head & Neck Surgery Baylor College of Medicine Houston Texas USA.ORCID https://orcid.org/0000-0002-1393-4174
Lauren M CassDepartment of Head and Neck Surgery Kaiser Permanente Portland Oregon USA.
Kevin J SykesDepartment of Otolaryngology - Head & Neck Surgery University of Kansas Medical Center Kansas City Kansas USA.ORCID https://orcid.org/0000-0001-9379-3406
Emily L CummingsDepartment of Internal Medicine Indiana University School of Medicine Indianapolis Indiana USA.ORCID https://orcid.org/0000-0003-4813-4473
Scott N FassasDepartment of Internal Medicine George Washington School of Medicine & Health Sciences Washington District of Columbia USA.ORCID https://orcid.org/0000-0002-2796-5449
Rohit NallaniDepartment of Otolaryngology - Head & Neck Surgery University of Kansas Medical Center Kansas City Kansas USA.ORCID https://orcid.org/0000-0001-6313-205X
Josh B SmithDepartment of Otolaryngology - Head & Neck Surgery St. Louis University School of Medicine St. Louis Missouri USA.
Alexander G ChiuDepartment of Otolaryngology - Head & Neck Surgery University of Kansas Medical Center Kansas City Kansas USA.
Jennifer A VillwockDepartment of Otolaryngology - Head & Neck Surgery University of Kansas Medical Center Kansas City Kansas USA.ORCID https://orcid.org/0000-0001-5645-4210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine the facilitators of and barriers to adherence to use of intranasal pharmacotherapy (daily intranasal corticosteroids and/or antihistamine, and nasal saline irrigation [NSI]), for allergic rhinitis (AR). Methods: Patients were recruited from an academic tertiary care rhinology and allergy clinic. Semi-structured interviews were conducted after the initial visit and/or 4-6 weeks following treatment. Transcribed interviews were analyzed using a grounded theory, inductive approach to elucidate themes regarding patient adherence to AR treatment. Results: A total of 32 patients (12 male, 20 female; age 22-78) participated (seven at initial visit, seven at follow-up visit, and 18 at both). Memory triggers, such as linking nasal routine to existing daily activities or medications, were identified by patients as the most helpful strategy for adherence at initial and follow-up visits. Logistical obstacles related to NSI (messy, takes time, etc.) was the most common concept discussed at follow-up. Patients modified the regimen based on side effects experienced or perceived efficacy. Conclusions: Memory triggers help patients adhere to nasal routines. Logistical obstacles related to NSI can deter from use. Health care providers should address both concepts during patient counseling. Nudge-based interventions that incorporate these concepts may help improve adherence to AR treatment. Level of Evidence: 2.

Indexed as

allergy/rhinologyendoscopyirrigationspatient reported outcome measurerhinitis

Identifiers

PMID36846400
PMCPMC9948570

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.