Evidence map›Paper›PMID 36846322›Full record

ArticleFrontiers in physiology2023

Piezo1 activation induces relaxation of the pudendal artery and corpus cavernosum.

Vanessa Dela Justina, Raiany Alves de Freitas, Olufunke O Arishe, Fernanda R Giachini, R Clinton Webb, Fernanda Priviero

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Pharmacology of PIEZO1 channels.British journal of pharmacology · 2024
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Vanessa Dela JustinaGraduate Program in Biological Sciences, Federal University of Goias, Goiânia, Goias, Brazil.
Raiany Alves de FreitasGraduate Program in Biological Sciences, Federal University of Goias, Goiânia, Goias, Brazil.
Olufunke O ArisheDepartment of Cell Biology and Anatomy-School of Medicine, University of South Carolina, Columbia, SC, United States.
Fernanda R GiachiniGraduate Program in Biological Sciences, Federal University of Goias, Goiânia, Goias, Brazil.
R Clinton WebbDepartment of Cell Biology and Anatomy-School of Medicine, University of South Carolina, Columbia, SC, United States.
Fernanda PrivieroDepartment of Cell Biology and Anatomy-School of Medicine, University of South Carolina, Columbia, SC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Piezo1 channel is a sensor for shear-stress in the vasculature. Piezo1 activation induces vasodilation, and its deficiency contributes to vascular disorders, such as hypertension. In this study, we aimed

Indexed as

cavernosal functionmechanosensoryPiezo1 channelshear-stressvascular function

Identifiers

PMID36846322
PMCPMC9950814

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.