Evidence map›Paper›PMID 36846255›Full record

ArticleFrontiers in veterinary science2023

Fecal identification markers impact the feline fecal microbiota.

Nora Jean Nealon, Alexandra Wood, Adam J Rudinsky, Hannah Klein, Matthew Salerno, Valerie J Parker, Jessica M Quimby, James Howard, Jenessa A Winston

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nora Jean NealonDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.
Alexandra WoodDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.
Adam J RudinskyDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.
Hannah KleinDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.
Matthew SalernoDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.
Valerie J ParkerDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.
Jessica M QuimbyDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, OH, United States.
James HowardDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.
Jenessa A WinstonDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Comparative Hepatobiliary and Intestinal Research Program, The Ohio State University, Columbus, OH, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal diagnostics are a mainstay of feline medicine, and fecal identification markers help to distinguish individuals in a multi-cat environment. However, the impact of identification markers on the fecal microbiota are unknown. Given the increased interest in using microbiota endpoints to inform diagnosis and treatment, the objective of this study was to examine the effects of orally supplemented glitter and crayon shavings on the feline fecal microbiota (amplicon sequencing of 16S rRNA gene V4 region). Fecal samples were collected daily from six adult cats that were randomized to receive oral supplementation with either glitter or crayon for two weeks, with a two-week washout before receiving the second marker. No adverse effects in response to marker supplementation were seen for any cat, and both markers were readily identifiable in the feces. Microbiota analysis revealed idiosyncratic responses to fecal markers, where changes in community structure in response to glitter or crayon could not be readily discerned. Given these findings, it is not recommended to administered glitter or crayon shavings as a fecal marker when microbiome endpoints are used, however their clinical use with other diagnostics should still be considered.

Indexed as

16S rRNAamplicon sequencingfecal markerfecal microbiotafecal samplefeline microbiotaveterinary medicine

Identifiers

PMID36846255
PMCPMC9946173

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.