ArticleFrontiers in pediatrics2023
Characteristics of immunological events in Epstein-Barr virus infection in children with infectious mononucleosis.
Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Article
- Network analysis of Mycoplasma pneumoniae pneumonia and Epstein-Barr virus co-infection.BMC infectious diseases · 2026Article
- Clinical characteristics in hospitalized children with infectious mononucleosis in Shanghai China: a single-center retrospective study.Italian journal of pediatrics · 2026Article
- Altered expression of the CD26/ADA axis in immune-mediated inflammation of infectious mononucleosis.Scientific reports · 2026Article
- The clinical utility of combining D-dimer with the C-reactive protein/albumin ratio for assessing treatment response in pediatric infectious mononucleosis.Frontiers in medicine · 2026Article
- Diagnostic value of combined flow cytometry-based detection of peripheral blood lymphocyte subsets and cytokines for pediatric infectious mononucleosis.Frontiers in pediatrics · 2026Article
- Alanine aminotransferase elevation in hospitalized children with infectious mononucleosis: independent associations with Epstein-Barr virus DNA load, age, and sex.Frontiers in pediatrics · 2026Article
- A routine blood parameter-based nomogram to predict prolonged fever in children with primary EBV infection.Frontiers in pediatrics · 2026Article
- Association between Epstein-Barr viral load and duration of hospitalization in pediatric infectious mononucleosis: a single-center retrospective study.Frontiers in medicine · 2026Article
- EBV-DNA viral load and lymphocyte subsets correlation in pediatric infectious mononucleosis with hepatic injury a retrospective cohort study.Frontiers in pediatrics · 2026Article
- Amoxicillin-Induced Hypersensitivity Versus Viral Exanthem in Epstein-Barr Virus Infection: A Paediatric Case Series.Cureus · 2025Article
- Epidemiological characteristics of infectious mononucleosis among hospitalized children in Henan Province, China: a retrospective study.BMC infectious diseases · 2025Article
- Elevated CD4⁺/CD8⁺ ratio and D-dimer as diagnostic biomarkers for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis versus infectious mononucleosis in children: a retrospective case-control study.BMC infectious diseases · 2025Article
- Elevated interleukin-10, -22, -24, and -26 in serum samples of children with infectious mononucleosis.Journal of medical biochemistry · 2025Article
- Knowledge mapping of childhood infectious mononucleosis: a bibliometric analysis for the twenty-first century.Journal of health, population, and nutrition · 2025Article
- Immunoregulatory therapy restores T cell subset balance and reveals risk factors for liver injury in children with infectious mononucleosis.American journal of translational research · 2025Article
- The diagnostic value of lymphocyte profiling for infectious mononucleosis and mycoplasma pneumoniae pneumonia.Frontiers in pediatrics · 2025Article
- The diagnostic value of peripheral blood lymphocyte testing in children with infectious mononucleosis.BMC pediatrics · 2024Article
- Liver injury and prolonged hospitalization as indicators of severity in patients with adenovirus infections.BMC infectious diseases · 2024Article
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Authors and funding
13 authors.
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Abstract
Backgrounds & aims: Epstein-Barr virus (EBV) infection occurs commonly in children and may cause acute infectious mononucleosis (AIM) and various malignant diseases. Host immune responses are key players in the resistance to EBV infection. We here assessed the immunological events and laboratory indicators of EBV infection, as well as determined the clinical usefulness of evaluating the severity and efficacy of antiviral therapy in AIM patients. Methods: We enrolled 88 children with EBV infection. The immune environment was defined by immunological events such as frequencies of lymphocyte subsets, phenotypes of T cells, and their ability to secrete cytokines, and so on. This environment was analyzed in EBV-infected children with different viral loads and in children in different phases of infectious mononucleosis (IM) from disease onset to convalescence. Results: Children with AIM had higher frequencies of CD3 Conclusion: Robust expansion of CD8
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