Evidence map›Paper›PMID 36846119›Full record

ArticleFrontiers in neurology2023

Predicting transient ischemic attack risk in patients with mild carotid stenosis using machine learning and CT radiomics.

Hai Xia, Lei Yuan, Wei Zhao, Chenglei Zhang, Lingfeng Zhao, Jialin Hou, Yancheng Luan, Yuxin Bi, Yaoyu Feng

Abstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Quality assessment of radiomics models in carotid plaque: a systematic review.Quantitative imaging in medicine and surgery · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hai XiaDepartment of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Lei YuanDepartment of Orthopedics, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Wei ZhaoImaging Intervention Center, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Chenglei ZhangDepartment of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Lingfeng ZhaoDepartment of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Jialin HouImaging Intervention Center, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yancheng LuanDepartment of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yuxin BiDepartment of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yaoyu FengDepartment of Vascular Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to establish a radiomics-based machine learning model that predicts the risk of transient ischemic attack in patients with mild carotid stenosis (30-50% North American Symptomatic Carotid Endarterectomy Trial) using extracted computed tomography radiomics features and clinical information. Methods: A total of 179 patients underwent carotid computed tomography angiography (CTA), and 219 carotid arteries with a plaque at the carotid bifurcation or proximal to the internal carotid artery were selected. The patients were divided into two groups; patients with symptoms of transient ischemic attack after CTA and patients without symptoms of transient ischemic attack after CTA. Then we performed random sampling methods stratified by the predictive outcome to obtain the training set ( Results: The random forest model that was built based on the radiomics and clinical feature information had the highest accuracy (area under curve = 0.879; 95% confidence interval, 0.787-0.979). The combined model outperformed the clinical model, whereas the combined model showed no significant difference from the radiomics model. Conclusion: The random forest model constructed with both radiomics and clinical information can accurately predict and improve discriminative power of computed tomography angiography in identifying ischemic symptoms in patients with carotid atherosclerosis. This model can aid in guiding the follow-up treatment of patients at high risk.

Indexed as

carotid arteryCT angiographymachine learningprediction modeltransient ischemic attack

Identifiers

PMID36846119
PMCPMC9944715

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.