Evidence map›Paper›PMID 36846053›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2023

Effectiveness and Safety of Lianhua Qingwen Capsules for COVID-19: A Propensity-Score Matched Cohort Study.

Yun Lu, Meng Zhang, Qing-Qing Yang, Wen-Jing Li, Kun Yang, Wen Hu, Su-Yu Gao, Qiao-Li Jiang, Li-Kai Lin, Hong Cheng and 1 more

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yun LuDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.ORCID https://orcid.org/0000-0002-0992-9399
Meng ZhangDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
Qing-Qing YangDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
Wen-Jing LiDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Kun YangDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Wen HuDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Su-Yu GaoDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Qiao-Li JiangDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Li-Kai LinInstitute of Hospital Management, Wuhan University, Wuhan 430071, China.
Hong ChengDepartment of Pharmacy, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.ORCID https://orcid.org/0000-0001-5807-3171
Feng SunDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.ORCID https://orcid.org/0000-0003-4334-6805

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a traditional Chinese medicine, Lianhua Qingwen capsules have been widely used to treat Coronavirus Disease 2019 (COVID-19). This study was aimed to demonstrate the association between treatment with Lianhua Qingwen capsules and the clinical outcomes of hospitalized patients with COVID-19. This retrospective study was conducted at four hospitals in Central China. Data of hospitalized COVID-19 patients were collected between December 19, 2019 and April 26, 2020. Based on whether Lianhua Qingwen capsules were used, patients were classified into Lianhua Qingwen and non-Lianhua Qingwen (control) groups. To control for confounding factors, we used conditional logistic regression in a propensity-score matched (PSM) cohort (1 : 1 balanced), as well as logistic regression without matching as sensitivity analysis. A total of 4918 patients were included, 2760 of whom received Lianhua Qingwen capsules and 2158 of whom did not. In the PSM model, after adjusting for confounders, the in-hospital mortality was similar between the Lianhua Qingwen group and the control group (6.8% vs. 3.3%, adjusted OR, 0.66 [95% CI, 0.38-1.15],

Identifiers

PMID36846053
PMCPMC9957644

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.