ArticleTransplantation direct2023
Normothermic Regional Perfusion Can Improve Both Utilization and Outcomes in DCD Liver, Kidney, and Pancreas Transplantation.
Article in Transplantation direct, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Normothermic regional perfusion in controlled donation after circulatory death liver transplantation: an updated systematic review and meta-analysis versus non-NRP and brain-death donors.Transplant international : official journal of the European Society for Organ Transplantation · 2026Pooled it
- Donor after circulatory death in pancreas transplantation: a scoping review of the literature.Frontiers in transplantation · 2025Pooled it
- Utilization and Outcomes of Septuagenarian Donation After Circulatory Death Donors.Transplantation direct · 2026Article
- The Association of Flavin Mononucleotide and Lactate During Normothermic Regional Perfusion with Post-Transplant Liver Outcomes: An Exploratory Study.Medicina (Kaunas, Lithuania) · 2026Article
- Donor Time to Death and DCD Liver Transplant Outcomes: Challenging the Dogma That Shorter Is Better.Transplantation direct · 2026Article
- Regulated cell death in organ transplantation: recent developments and mechanistic overview.Journal of molecular cell biology · 2026Review
- Normothermic Regional Perfusion in Controlled Donation After Circulatory Death: Growing Evidence for Liver Transplantation.Clinical transplantation · 2026Review
- Patient perspectives on the ethics and acceptability of perfusion techniques for organ transplantation: a qualitative study.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Geographic variation in utilization of deceased donor livers in the United States in the era of advanced perfusion.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2026Article
- Advancements inFrontiers in transplantation · 2026Review
- Implementation of a controlled DCD program in Western Austria - key considerations and insights.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Utilization of Liver Grafts From Donation After Circulatory Death Donors on Extracorporeal Membrane Oxygenation Support Using Normothermic Regional Perfusion.Transplantation direct · 2025Article
- The Landscape of In Situ and Ex Situ Machine Perfusion Utilization for Liver Grafts From Noncardiac Donation After Circulatory Death Donors in the Early era of Machine Perfusion in the United States.Transplantation direct · 2025Article
- Emerging National Trends in Normothermic Regional Perfusion for Simultaneous Pancreas-Kidney Transplantation.Clinical transplantation · 2025Article
- Novel pulmonary abdominal normothermic regional perfusion circuit for simultaneous in-donor evaluation and preservation of lungs and abdominal organs in donation after circulatory death.General thoracic and cardiovascular surgery · 2025Article
- Update on Organ Allocation and Liver Transplantation.Gastroenterology & hepatology · 2025Article
- Thoracoabdominal normothermic regional perfusion: Is it ethical?Monash bioethics review · 2025Article
- Recent Strategies to Attenuate Hepatocellular Carcinoma Recurrence After Liver Transplantation: A Narrative Review.Cancers · 2025Review
- Thoracoabdominal Normothermic Regional Perfusion: Real-world Experience and Outcomes of DCD Liver Transplantation.Transplantation direct · 2025Article
- Thoracoabdominal Normothermic Regional Perfusion and Donation After Circulatory Death Lung Use.JAMA network open · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Normothermic regional perfusion (NRP) has gained widespread adoption in multiple European countries. The aim of this study was to examine the influence of thoracoabdominal-NRP (TA-NRP) on the utilization and outcomes of liver, kidney, and pancreas transplantation in the United States. Methods: Using the US national registry data between 2020 and 2021, donation after circulatory death (DCD) donors were separated into 2 groups: DCD with TA-NRP and without TA-NRP. There were 5234 DCD donors; among them 34 donors were with TA-NRP. After 1:4 propensity score matching, the utilization rates were compared between DCD with and without TA-NRP. Results: Although the utilization rates of kidney and pancreas were comparable ( Conclusions: TA-NRP in the United States significantly increased the utilization rate of abdominal organs from DCD donors with comparable outcomes after transplantation. Increasing use of NRP may expand the donor pool without compromising transplant outcomes.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.