Case report: a transcatheter aortic valve replacement failure secondary to COVID-19 infection.

P Ryan Tacon, Louie Cao, Kade Birkeland, Ilan Kedan

Abstract readCase Reports

In one paragraph

Article in European heart journal. Case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Early TAVR Explantation Due to a Large Mobile Leaflet Mass and Severe Prosthetic Valve Stenosis.JACC. Case reports · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

P Ryan TaconCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Louie CaoCedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Kade BirkelandEnterprise Data Intelligence, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

Ilan KedanSmidt Cedars Sinai Heart Institute, Wilshire Blvd Suite 200, Beverly Hills, Los Angeles, CA 90048, USA.ORCID https://orcid.org/0000-0002-0871-3713

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Valve thrombosis is a well-documented cause of bioprosthetic valve failure. Case reports have been published of prosthetic valve thrombosis secondary to COVID-19 infection. This is the first case report of COVID-19 associated valve thrombosis in a patient with transcatheter aortic valve replacement (TAVR). Case summary: A 90-year-old female with atrial fibrillation on therapeutic apixaban and status-post TAVR presented with COVID-19 infection and was found to have severe bioprosthetic valvular regurgitation with features suggestive of valve thrombosis. She underwent valve-in-valve TAVR with resolution of valvular dysfunction. Discussion: This case report contributes to a growing body of evidence describing the occurrence of thrombotic complications in patients with valve replacement and COVID-19 infection. Increased vigilance and continued investigation are warranted to better characterize thrombotic risk and to inform optimal antithrombotic strategies during COVID-19 infection.

Indexed as

Acute heart failureAortic valveCase reportProsthetic valve thrombosisPulmonary oedemaThrombosisValve replacement

Identifiers

PMID36845835

DOI10.1093/ehjcr/ytad054

PMCPMC9949707

What OpenQuestion holds

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LicenceCC BY-NC

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.