Evidence map›Paper›PMID 36845686›Full record

ArticleFrontiers in oncology2023

Targeted O-glycoproteomics for the development of diagnostic markers for advanced colorectal cancer.

Daisuke Takakura, Shoko Ohashi, Noritoshi Kobayashi, Motohiko Tokuhisa, Yasushi Ichikawa, Nana Kawasaki

Abstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daisuke TakakuraGraduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.
Shoko OhashiGraduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.
Noritoshi KobayashiDepartment of Oncology, Yokohama City University Hospital, Yokohama, Japan.
Motohiko TokuhisaDepartment of Oncology, Yokohama City University Hospital, Yokohama, Japan.
Yasushi IchikawaDepartment of Oncology, Yokohama City University Hospital, Yokohama, Japan.
Nana KawasakiGraduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant glycosylation is a prominent feature of cancer, that can be used as targets to improve the existing cancer biomarkers, and help to assess metastasis risks, and therapeutic effects. We developed a targeted O-glycoproteomics method using serum specimens, and evaluated its utility in identifying advanced colorectal cancer (CRC) markers. To this end, we combined consecutive lectin affinity purification using

Indexed as

colorectal cancerglycoproteinsglycosylationLC/MS/MSO-glycoproteomicsserum diagnostic marker

Identifiers

PMID36845686
PMCPMC9948623

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.