ArticleFrontiers in aging neuroscience2023
Whole body-electromyostimulation effects on serum biomarkers, physical performances and fatigue in Parkinson's patients: A randomized controlled trial.
Article in Frontiers in aging neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04878679 (Effects of Combined Whole Body Electromiostimulation), which is not on this map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Combined Whole Body Electromiostimulation (WB-EMS) and Dynamic Movements on Motor and Cognitive Performance, Neurotrophic Factors and Alpha-synuclein in Parkinson's Disease
Who cites it
10 citing papers in PubMed.
- Intensive multidisciplinary rehabilitation modulates serumFrontiers in cellular neuroscience · 2026Article
- Interaction Between α-Synuclein and DJ-1 in Parkinson's Disease.Brain sciences · 2025Review
- Exploring the feasibility of combining transcutaneous electrical spinal cord stimulation and overground robotic exoskeleton for gait rehabilitation in patients with spinal cord injury.Frontiers in neurology · 2025Article
- Targeting neuroplasticity: a viewpoint on a future research direction with Parkinson's disease-related fatigue.Frontiers in aging neuroscience · 2025Article
- Enhancing Physical and Cognitive Efficiency in Elderly Individuals at Risk for Dementia Using Whole-Body Electrostimulation: A Randomized Controlled Trial.Journal of functional morphology and kinesiology · 2024Article
- Effects and Mechanisms of Exercise on Brain-Derived Neurotrophic Factor (BDNF) Levels and Clinical Outcomes in People with Parkinson's Disease: A Systematic Review and Meta-Analysis.Brain sciences · 2024Review
- Non-Athletic Cohorts Enrolled in Longitudinal Whole-Body Electromyostimulation Trials-An Evidence Map.Sensors (Basel, Switzerland) · 2024Review
- Revised contraindications for the use of non-medical WB-electromyostimulation. Evidence-based German consensus recommendations.Frontiers in sports and active living · 2024Review
- Acute Effects of Combining Whole-Body Electromyostimulation with Resistance Training in Active Women.Journal of functional morphology and kinesiology · 2023Article
- Long-Term Physical Activity Effectively Reduces the Consumption of Antihypertensive Drugs: A Randomized Controlled Trial.Journal of cardiovascular development and disease · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Whole-body electromyostimulation (WB-EMS) was never previously applied to Parkinson's disease (PD) patients. This randomized controlled study aimed to find the most effective and safe WB-EMS training protocol for this population. Methods: Twenty-four subjects (age: 72.13 ± 6.20 years), were randomly assigned to three groups: a high-frequency WB-EMS strength training group (HFG) (rectangular stimulation at 85 Hz, 350 μs, 4 s stimulation/4 s rest), a low-frequency WB-EMS aerobic training group (LFG) (rectangular stimulation 7 Hz, 350 μs, with a continuous pulse duration), and an inactive control group (CG). Participants of the two experimental groups underwent 24 controlled WB-EMS training sessions, with a duration of 20 min each, during 12-week intervention. Serum growth factors (BDNF, FGF-21, NGF and proNGF), α-synuclein, physical performance and Parkinson's Disease Fatigue Scale (PFS-16) responses were analyzed to evaluate the pre-post variation and differences among groups. Results: Significant interactions of Time*Groups were detected for BDNF (Time*Groups Conclusion: LFG training was the best choice for improving or maintaining physical performance, fatigue perception and variation in serum biomarkers. Clinical trial registration: https://www.clinicaltrials.gov/ct2/show/NCT04878679, identifier NCT04878679.
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