Evidence map›Paper›PMID 36845638›Full record

Trial reportBioMed research international2023

Construction and Verification of a Risk Prediction Model for the Occurrence of Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage Requiring Mechanical Ventilation.

Xianjun Chen, Yue Ou, Jingxing Leng, Changfeng Wang, Feixiang Min, Yinghua Xia, Gui Yu, Hui Xiang, Ru'en Liu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BioMed research international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xianjun ChenMedical College of Nanchang University, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0003-2041-2638
Yue OuMedical College of Nanchang University, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0001-5616-1274
Jingxing LengDepartment of Neurosurgery, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0002-2626-1693
Changfeng WangMedical College of Nanchang University, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0001-6646-9811
Feixiang MinMedical College of Nanchang University, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0003-0970-7857
Yinghua XiaMedical College of Nanchang University, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0002-7720-4963
Gui YuDepartment of Neurosurgery, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0003-3070-700X
Hui XiangDepartment of Neurosurgery, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0002-2085-2601
Ru'en LiuDepartment of Neurosurgery, Jiangxi Provincial People's Hospital, Nanchang, Jiangxi 330006, China.ORCID https://orcid.org/0000-0002-2405-5597

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Delayed cerebral ischemia (DCI) contributes to poor aneurysm prognosis. Subarachnoid hemorrhage and DCI have irreversible and severe consequences once they occur; therefore, early prediction and prevention are important. We investigated the risk factors for postoperative complications of DCI in patients with aneurysmal subarachnoid hemorrhage (aSAH) requiring mechanical ventilation in intensive care and validated a prediction model. Methods: We retrospectively analyzed patients with aSAH who were treated in a French university hospital neuro-ICU between January 2010 and December 2015. The patients were randomized into a training group (144) and verification groups (60). Nomograms were validated in the training and verification groups, where receiver operating characteristic curve analysis was used to verify model discrimination; calibration curve and Hosmer-Lemeshow test were used to determine model calibration; and decision curve analysis (DCA) was used to verify clinical validity of the model. Results: External ventricular drain (EVD), duration of mechanical ventilation, and treatment were significantly associated in the univariate analysis; EVD and rebleeding were significantly associated with the occurrence of DCI after aSAH. Binary logistic regression was used to select five clinicopathological characteristics to predict the occurrence of DCI in patients with aSAH requiring mechanical ventilation nomograms of the risk of DCI. Area under the curve values for the training and verification groups were 0.768 and 0.246, with Brier scores of 0.166 and 0.163, respectively. Hosmer-Lemeshow calibration test values for the training and verification groups were Conclusions: The predictive model of concurrent DCI in aSAH has theoretical and practical values and can provide individualized treatment options for patients with aSAH who require mechanical ventilation.

Indexed as

Brain IschemiaSubarachnoid HemorrhageCerebral InfarctionHumansRespiration, ArtificialRetrospective Studies

Identifiers

PMID36845638
PMCPMC9957647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.