Evidence map›Paper›PMID 36845536›Full record

ArticleBio-protocol2023

Comprehensive Analyses of Muscle Function, Lean and Muscle Mass, and Myofiber Typing in Mice.

Hima Bindu Durumutla, Chiara Villa, Manoj Panta, Michelle Wintzinger, Ashok Daniel Prabakaran Pragasam, Karen Miz, Mattia Quattrocelli

Open access · diamondAbstract read
In one paragraph

Article in Bio-protocol, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Role of Peptides in Skeletal Muscle Wasting: A Scoping Review.Journal of cachexia, sarcopenia and muscle · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hima Bindu DurumutlaDivision of Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Chiara VillaDivision of Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Manoj PantaDivision of Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Michelle WintzingerDivision of Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Ashok Daniel Prabakaran PragasamDivision of Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Karen MizDivision of Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Mattia QuattrocelliDivision of Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Cincinnati Children's Hospital Medical Center · US

Funding

Coordinated mechanisms to rescue bioenergetics and sarcopenia in agingR01AG078174 · NIA · CINCINNATI CHILDRENS HOSP MED CTR · PI QUATTROCELLI, MATTIA · 2022 to 2025
$1.3M
Harnessing novel glucocorticoid biology to treat diabetic cardiomyopathyR01HL166356 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI QUATTROCELLI, MATTIA · 2023 to 2025
$1.2M
Glucocorticoid and circadian clock coregulation of insulin sensitivity and metabolismK01DK121875 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI QUATTROCELLI, MATTIA · 2019 to 2021
$444k
CHRONO-MECHANISMS of CARDIOMETABOLIC PHARMACOLOGYR56HL158531 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI QUATTROCELLI, MATTIA · 2021 to 2021
$398k
ROLE OF CIRCADIAN RHYTHM AND INTERMITTENT DOSING IN MUSCLE TRIGLYCERIDE LIPASE INDUCTION BY GLUCOCORTICOIDSR03DK130908 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI QUATTROCELLI, MATTIA · 2022 to 2023
$249k
NHLBI NIH HHS R01 HL166356NHLBI NIH HHS R56 HL158531NIA NIH HHS R01 AG078174NIDDK NIH HHS K01 DK121875NIDDK NIH HHS R03 DK130908
6 · The paper itself

Abstract

Skeletal muscle disorders commonly affect the function and integrity of muscles. Novel interventions bring new potential to rescue or alleviate the symptoms associated with these disorders. In vivo and in vitro testing in mouse models allows quantitative evaluation of the degree of muscle dysfunction, and therefore, the level of potential rescue/restoration by the target intervention. Several resources and methods are available to assess muscle function and lean and muscle mass, as well as myofiber typing as separate concepts; however, a technical resource unifying these methods is missing. Here, we provide detailed procedures for analyzing muscle function, lean and muscle mass, and myofiber typing in a comprehensive technical resource paper. Graphical abstract.

Indexed as

Lean and muscle massMuscle cross sectional areaMuscle forceMuscle functionMyofiber typeSkeletal muscle

Identifiers

PMID36845536
PMCPMC9947547
OpenAlexW4320923537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.