Evidence map›Paper›PMID 36844898›Full record

ArticleJournal of oral microbiology2023

Saliva microbiome alterations in dental fluorosis population.

Shanshan Liu, Qiangsheng Song, Chenchen Zhang, Mengwan Li, Zhenzhen Li, Yudong Liu, Li Xu, Xiaofei Xie, Lili Zhao, Rongxiu Zhang and 4 more

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Shanshan LiuDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Qiangsheng SongDepartment of Stomatology, Huaiyuan county people's Hospital, Bengbu, China.
Chenchen ZhangDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Mengwan LiDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Zhenzhen LiDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Yudong LiuDepartment of Histology and Embryology, Bengbu Medical College, Bengbu, China.
Li XuDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Xiaofei XieDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Lili ZhaoDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Rongxiu ZhangDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Qinglong WangDepartment of Stomatology, Bengbu Medical College, Bengbu, China.
Guojin ZengDepartment of Stomatology, Bengbu Medical College, Bengbu, China.
Yifan ZhangDepartment of Stomatology, Bengbu Medical College, Bengbu, China.
Kai ZhangDepartment of Stomatology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.ORCID https://orcid.org/0000-0001-7850-7643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We aimed to explore saliva microbiome alterations in dental fluorosis population. Methods: The prevalence of dental fluorosis was examined in 957 college students. Dean's fluorosis index was used to evaluate the dental fluorosis status. Changes in the composition of the salivary microbiome were assessed in a subset of these patients (100 healthy controls, 100 dental fluorosis patients). Results: Dental fluorosis affected 47% of the student sample, and incidence was unrelated to gender. Compared with healthy controls, the microbiota of patients with dental fluorosis exhibited increased diversity, with increased abundance of Conclusions: These results suggest that there are striking differences in salivary microbiome between healthy controls and dental fluorosis patients. Dental fluorosis may contribute to periodontitis and systemic lung diseases. There is a need for cohort studies to determine whether altering the salivary microbiota in dental fluorosis patients can alter the development of oral or systemic diseases.

Indexed as

biomarkerdental fluorosisMicrobiomepopulationsaliva

Identifiers

PMID36844898
PMCPMC9946311

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.