Evidence map›Paper›PMID 36844735›Full record

ArticleFrontiers in cardiovascular medicine2023

Relationship between baseline D-dimer and prognosis in Japanese patients with venous thromboembolism: Insights from the J'xactly study.

Shohei Migita, Yasuo Okumura, Ikuo Fukuda, Mashio Nakamura, Norikazu Yamada, Morimasa Takayama, Hideaki Maeda, Takeshi Yamashita, Takanori Ikeda, Makoto Mo and 2 more

Abstract read
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In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Nomogram for Risk of Secondary Venous Thromboembolism in Stroke Patients: A Study Based on the MIMIC-IV Database.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shohei MigitaDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
Yasuo OkumuraDivision of Cardiology, Department of Medicine, Nihon University School of Medicine, Tokyo, Japan.
Ikuo FukudaDepartment of Cardiology, Keimeikai Yokawa Hospital, Miki, Japan.
Mashio NakamuraNakamura Medical Clinic, Kuwana, Japan.
Norikazu YamadaDepartment of Cardiology, Kuwana City Medical Center, Kuwana, Japan.
Morimasa TakayamaDepartment of Cardiology, Sakakibara Heart Institute, Fuchu, Japan.
Hideaki MaedaDepartment of Heart and Vascular Center, Ukima Central Hospital, Tokyo, Japan.
Takeshi YamashitaDepartment of Cardiovascular Medicine, The Cardiovascular Institute, Tokyo, Japan.
Takanori IkedaDepartment of Cardiovascular Medicine, Toho University Faculty of Medicine, Tokyo, Japan.
Makoto MoDepartment of Cardiovascular Surgery, Yokohama Minami Kyosai Hospital, Yokohama, Japan.
Tsutomu YamazakiInnovation and Research Support Center, International University of Health and Welfare, Tokyo, Japan.
Atsushi HirayamaDepartment of Cardiology, Osaka Police Hospital, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: D-dimer is a biomarker of fibrin production and degradation, and changes in D-dimer concentration suggest fibrin clot formation, which is associated with thromboembolism and hypercoagulable states. Thus, an elevated D-dimer concentration could be a useful prognostic predictor for patients with venous thromboembolism (VTE). Methods and results: In this subanalysis of the J'xactly study, a prospective multicenter study conducted in Japan, we examined the clinical outcomes of 949 patients with VTE stratified by baseline D-dimer concentration. The median D-dimer concentration was 7.6 μg/ml (low D-dimer group: <7.6 μg/ml [ Conclusion: Elevated D-dimer concentration may be an important prognostic predictor in Japanese patients with VTE.

Indexed as

anticoagulantbleedingrecurrencerivaroxabanvenous thromboembolism

Identifiers

PMID36844735
PMCPMC9949378

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.