Evidence map›Paper›PMID 36844718›Full record

ArticleFrontiers in cardiovascular medicine2023

Individual and combined contributions of non-high-density lipoprotein cholesterol and brachial-ankle pulse wave velocity to cardiovascular disease risk: Results of a prospective study using the Kailuan cohort.

Qiongbing Zheng, Hui Wang, Xianxuan Wang, Youmian Lan, Weiqiang Wu, Xinran Yu, Zegui Huang, Zekai Chen, Zefeng Cai, Qi Lin and 7 more

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In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Qiongbing ZhengDepartment of Neurology, Shantou Central Hospital, Shantou, China.
Hui WangSchool of Nursing, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China.
Xianxuan WangGraduate School, Shantou University Medical College, Shantou, Guangdong, China.
Youmian LanGraduate School, Shantou University Medical College, Shantou, Guangdong, China.
Weiqiang WuGraduate School, Shantou University Medical College, Shantou, Guangdong, China.
Xinran YuGraduate School, North China University of Science and Technology, Tangshan, China.
Zegui HuangGraduate School, Shantou University Medical College, Shantou, Guangdong, China.
Zekai ChenDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Zefeng CaiDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.
Qi LinDepartment of Neurology, Shantou Central Hospital, Shantou, China.
Houshi ZhouDepartment of Neurology, Shantou Central Hospital, Shantou, China.
Yongdong ZhuDepartment of Neurology, Shantou Central Hospital, Shantou, China.
Muyuan LiuDepartment of Head and Neck, Cancer Hospital of Shantou University Medical College, Shantou, China.
Kuangyi WuGraduate School, Shantou University Medical College, Shantou, Guangdong, China.
Huancong ZhengGraduate School, Shantou University Medical College, Shantou, Guangdong, China.
Shouling WuDepartment of Cardiology, Kailuan General Hospital, Tangshan, China.
Youren ChenDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aimed to characterize the relationship of a combination of circulating non-high-density lipoprotein-cholesterol (non-HDL-C) concentration and brachial-ankle pulse wave velocity (baPWV) with cardiovascular disease (CVD). Methods: We performed a prospective cohort study of the residents of the Kailuan community, with data from a total of 45,051 participants being included in the final analysis. The participants were allocated to four groups according to their non-HDL-C and baPWV status, each of which was categorized as high or normal. Cox proportional hazards models were used to explore the relationships of non-HDL-C and baPWV, individually and in combination, with the incidence of CVD. Results: During the 5.04-year follow-up period, 830 participants developed CVD. Compared with the Normal non-HDL-C group independently, the multivariable adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for CVD in the High non-HDL-C was 1.25 (1.08-1.46). Compared with the Normal baPWV group independently, the HRs and 95% CIs for CVD in the High baPWV was 1.51 (1.29-1.76). In addition, compared with the Normal both non-HDL-C and baPWV group, the HRs and 95% CIs for CVD in the High non-HDL-C and normal baPWV, Normal non-HDL-C and high baPWV, and High both non-HDL-C and baPWV groups were 1.40 (1.07-1.82), 1.56 (1.30-1.88), and 1.89 (1.53-2.35), respectively. Conclusion: High non-HDL-C concentration and high baPWV are independently associated with a higher risk of CVD, and individuals with high both non-HDL-C and baPWV are at a still higher risk of CVD.

Indexed as

brachial-ankle pulse wave velocitycardiovascular diseasescombined effectKailuan cohortnon-high-density lipoprotein cholesterol

Identifiers

PMID36844718
PMCPMC9947564

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