Evidence map›Paper›PMID 36844630›Full record

ArticleOncology letters2023

Genetic variants of cancer‑associated genes analyzed using next‑generation sequencing in small sporadic vestibular schwannomas.

Takeshi Fujita, Kazuko Sakai, Natsumi Uehara, Yujiro Hoshi, Anjin Mori, Hajime Koyama, Mitsuo Sato, Kazuya Saito, Yasuhiro Osaki, Kazuto Nishio and 1 more

Abstract read
In one paragraph

Article in Oncology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Case Report: SomaticFrontiers in oncology · 2026
    Article
  2. Article
  3. Sporadic pediatric vestibular schwannoma: a case report in a 4-year-old boy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Takeshi FujitaDepartment of Otolaryngology Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo 650-0017, Japan.
Kazuko SakaiDepartment of Genome Biology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka 589-8511, Japan.
Natsumi UeharaDepartment of Otolaryngology Head and Neck Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo 650-0017, Japan.
Yujiro HoshiDepartment of Otorhinolaryngology, Mitsui Memorial Hospital, Tokyo 101-8643, Japan.
Anjin MoriDepartment of Otorhinolaryngology - Head and Neck Surgery, NTT Medical Center Tokyo, Tokyo 141-8625, Japan.
Hajime KoyamaDepartment of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo Hospital, Tokyo 113-8655, Japan.
Mitsuo SatoDepartment of Otolaryngology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka 589-8511, Japan.
Kazuya SaitoDepartment of Otorhinolaryngology, Izumi City General Hospital, Izumi, Osaka 594-0073, Japan.
Yasuhiro OsakiDepartment of Otolaryngology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka 589-8511, Japan.
Kazuto NishioDepartment of Genome Biology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka 589-8511, Japan.
Katsumi DoiDepartment of Otolaryngology, Kindai University Faculty of Medicine, Osaka-Sayama, Osaka 589-8511, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vestibular schwannoma (VS) is the most common tumor of the cerebellopontine angle. Despite the increasing diagnosis of sporadic VS over the past decade, the use of traditional microsurgeries to treat VS has decreased. This is likely a result of the adoption of serial imaging as the most common initial evaluation and treatment strategy, especially for small-sized VS. However, the pathobiology of VSs remains unclear, and elucidating the genetic information of tumor tissue may reveal novel insights. The present study performed a comprehensive genomic analysis of all exons in the key tumor suppressor and oncogenes from 10 small (<15 mm) sporadic VS samples. The evaluations identified

Indexed as

acoustic neuromaneurofibromatosis 2NF2NGSvestibular schwannoma

Identifiers

PMID36844630
PMCPMC9950330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.