Evidence map›Paper›PMID 36844430›Full record

ArticleJournal of biomedical optics2023

Donggyu Kim, Joongho Ahn, Eunwoo Park, Jin Young Kim, Chulhong Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomedical optics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
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  8. Non-Invasive Photoacoustic Cerebrovascular Monitoring of Early-Stage Ischemic Strokes In Vivo.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Donggyu KimPohang University of Science and Technology, Departments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, Medical Science and Engineering, and Medical Device Innovation Center Group, Pohang, Republic of Korea.
Joongho AhnPohang University of Science and Technology, Departments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, Medical Science and Engineering, and Medical Device Innovation Center Group, Pohang, Republic of Korea.
Eunwoo ParkPohang University of Science and Technology, Departments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, Medical Science and Engineering, and Medical Device Innovation Center Group, Pohang, Republic of Korea.ORCID 0000-0001-7954-7911
Jin Young KimPohang University of Science and Technology, Departments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, Medical Science and Engineering, and Medical Device Innovation Center Group, Pohang, Republic of Korea.
Chulhong KimPohang University of Science and Technology, Departments of Electrical Engineering, Convergence IT Engineering, Mechanical Engineering, Medical Science and Engineering, and Medical Device Innovation Center Group, Pohang, Republic of Korea.ORCID 0000-0001-7249-1257
Pohang University of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Corticosteroids-commonly prescribed medications for skin diseases-inhibit the secretion of vasodilators, such as prostaglandin, thereby exerting anti-inflammatory action by constricting capillaries in the dermis. The effectiveness of corticosteroids is determined by the degree of vasoconstriction followed by skin whitening, namely, the blanching effect. However, the current method of observing the blanching effect indirectly evaluates the effects of corticosteroids. Aim: In this study, we employed optical-resolution photoacoustic (PA) microscopy (OR-PAM) to directly visualize the blood vessels and quantitatively evaluate vasoconstriction. Approach: Using OR-PAM, the vascular density in mice skin was monitored for 60 min after performing each experimental procedure for four groups, and the vasoconstriction was quantified. Volumetric PA data were segmented into the papillary dermis, reticular dermis, and hypodermis based on the vascular characteristics obtained through OR-PAM. The vasoconstrictive effect of each skin layer was quantified according to the dermatological treatment method. Results: In the case of corticosteroid topical application, vasoconstriction was observed in the papillary ( Conclusions: Our results indicate that OR-PAM can quantitatively monitor the vasoconstriction induced by corticosteroids, thereby validating OR-PAMs potential as a practical evaluation tool for predicting the effectiveness of corticosteroids in dermatology.

Indexed as

Anti-Inflammatory AgentsPhotoacoustic TechniquesAdrenal Cortex HormonesAnimalsMiceSkinSpectrum AnalysisVasoconstrictionAdrenal Cortex HormonesAnti-Inflammatory Agentscorticosteroidoptical-resolution photoacoustic microscopyphotoacoustic imagingskin anatomyvasoconstriction

Identifiers

PMID36844430
PMCPMC9951467
OpenAlexW4321782173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.