Evidence map›Paper›PMID 36844150›Full record

ArticleBrain communications2023

A new class of peptides from wasp venom: a pathway to antiepileptic/neuroprotective drugs.

Márcia Renata Mortari, Alexandra O S Cunha, Lilian C Dos Anjos, Henrique O Amaral, Maria Varela Torres Quintanilha, Erica A Gelfuso, Mauricio Homem-de-Mello, Hugo de Almeida, Solange Rego, Bernard Maigret and 2 more

Abstract read
In one paragraph

Article in Brain communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Márcia Renata MortariNeuropharmacology Laboratory, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília, Brasília 71910-900, Brazil.ORCID https://orcid.org/0000-0002-6849-6001
Alexandra O S CunhaNeurobiology and Venoms Laboratory, Department of Biology, Faculty of Philosophy, Sciences and Literature of Ribeirão Preto, University of São Paulo, São Paulo 14040-900, Brazil.
Lilian C Dos AnjosNeuropharmacology Laboratory, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília, Brasília 71910-900, Brazil.
Henrique O AmaralNeuropharmacology Laboratory, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília, Brasília 71910-900, Brazil.
Maria Varela Torres QuintanilhaNeuropharmacology Laboratory, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília, Brasília 71910-900, Brazil.
Erica A GelfusoNeuropharmacology Laboratory, Department of Physiological Sciences, Institute of Biological Sciences, University of Brasília, Brasília 71910-900, Brazil.
Mauricio Homem-de-Melloin Silico Toxicology Laboratory (inSiliTox), Department of Pharmacy, Health Sciences School, University of Brasilia, Brasilia 71910-900, Brazil.
Hugo de AlmeidaTeam CAPSID, Laboratoire Lorrain de Recherche en Informatique et ses applications (LORIA), Vandoeuvre Les Nancy F-54506, France.
Solange RegoTeam CAPSID, Laboratoire Lorrain de Recherche en Informatique et ses applications (LORIA), Vandoeuvre Les Nancy F-54506, France.
Bernard MaigretTeam CAPSID, Laboratoire Lorrain de Recherche en Informatique et ses applications (LORIA), Vandoeuvre Les Nancy F-54506, France.
Norberto P LopesOrganic Chemistry Laboratory, Department of Physics and Chemistry, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, São Paulo 14040-900, Brazil.
Wagner F Dos SantosNeurobiology and Venoms Laboratory, Department of Biology, Faculty of Philosophy, Sciences and Literature of Ribeirão Preto, University of São Paulo, São Paulo 14040-900, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of venom-derived peptides to disrupt physiological processes in mammals provides an exciting source for pharmacological development. Our research group has identified a new class of neuroactive peptides from the venom of a Brazilian social wasp,

Indexed as

antiepileptic drugepilepsyneuropeptidesneuroprotectionWasp venoms

Identifiers

PMID36844150
PMCPMC9945850

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.